Table 3.
In Vitro deposition tests—emitted dose (ED), fine particle dose (FPD), and fine particle fraction (FPF) of salbutamol sulphate from ternary mixtures of α-lactose monohydrate (Lα·H2O), salbutamol sulphate (SS), and variable percentages (10%, 30%, and 50% w/w) of micronized lactose in comparison with a binary mixture containing no micronized lactose (M-SS). Mean values ± standard deviation (n = 5).
| Mixture | ED (µg) | FPD (µg) | FPF (%) |
|---|---|---|---|
| M-SS | 177.1 ± 3.4 | 26.8 ± 1.9 | 15.1 ± 0.8 |
| M-10 | 178.7 ± 4.6 | 84.3 ± 2.6 | 47.2 ± 0.7 |
| M-30 | 180.9 ± 9.7 | 103.4 ± 7.3 | 57.2 ± 2.5 |
| M-50 | 102.8 ± 5.5 | 34.9 ± 4.6 | 33.9 ± 2.8 |