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Gene knockdown of transcription factor acting on the MITF-M promoter. RT-PCR analysis of MITF-M. B16-F0 cells were transfected with siRNA against CREB (A), CRTC1 (B), SOX10 (C) or β-catenin (D) for 48 h and stimulated with SCF for 2 h. Data are mean ± SEM. #P < 0.05 vs. scrambled siRNA. Abbreviation; n.s., not significant.
