Table 2.
Mean Perfusion | MTT | VoD | LDH Activity | LDH mRNA | MCT1 | MCT4 | ||
---|---|---|---|---|---|---|---|---|
mL/100 mL/Min | s | mL/100 mL | Ratio | U/μg | LDH/RPL22 Ratio | MCT1/RPL22 Ratio | MCT4/RPL22 Ratio | |
Placenta 1 | 40.8 | 31.2 | 17.8 | 0.034 | 15e3 ± 11e3 | 0.19 ± 0.09 | 1.6 ± 1.4 | 0.02 ± 0.01 |
Placenta 2 | 41.1 | 14.6 | 9.5 | 0.018 | 2e3 ± 1e3 | 0.06 ± 0.03 | 1.5 ± 0.4 | 0.01 ± 0.01 |
Placenta 3 | 43.8 | 32.6 | 23.0 | 0.052 | 14e3 ± 11e3 | 0.12 ± 0.11 | 2.2 ± 0.6 | 0.01 ± 0.02 |
Abbreviations: MTT, mean perfusion, mean transit time; VoD, volume of distribution; AUC, lactate-to-pyruvate area under curve ratio. Ex Vivo Biopsy Assays. Lactate dehydrogenase (LDH) Activity and LDH mRNA Expression. Monocarboxylate transporter (MCT) 1 and MCT4 mRNA Expression.