TABLE 4.
Variables | Model 1 |
Model 2 |
Model 3 |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
SHR | 95% CI | P value | SHR | 95% CI | P value | SHR | 95% CI | P value | |||
Model 1 | |||||||||||
Race/ethnicity | 0.028b | 0.023c | 0.005d | ||||||||
Non-Hispanic white | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | ||
Non-Hispanic African American | 1.356 | 0.920–2.000 | 0.124 | 1.557 | 1.029–2.356 | 0.036 | 1.924 | 1.245–2.975 | 0.003 | ||
Hispanic | 1.988 | 1.226–3.223 | 0.005 | 1.971 | 1.198–3.243 | 0.008 | 2.253 | 1.313–3.869 | 0.003 | ||
Other minorities | 1.692 | 0.977–2.930 | 0.061 | 1.757 | 0.958–3.224 | 0.069 | 1.558 | 0.824–2.944 | 0.172 | ||
Model 2 | |||||||||||
Other demographic characteristics | |||||||||||
Marital status (not married) | 0.614 | 0.427–0.884 | 0.009 | 0.612 | 0.412–0.908 | 0.015 | |||||
Occupation (>skilled manual worker) | NS | 0.706 | 0.493–1.010 | 0.057 | |||||||
Study location | 0.002e | 0.021f | |||||||||
Site A | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | |||||
Site B | 1.926 | 1.125–3.300 | 0.017 | 1.720 | 0.983–3.009 | 0.057 | |||||
Site C | 0.677 | 0.402–1.138 | 0.141 | 0.840 | 0.480–1.471 | 0.543 | |||||
Site D | 1.494 | 0.885–2.522 | 0.133 | 1.502 | 0.864–2.612 | 0.149 | |||||
Medical factors | |||||||||||
Charlson Comorbidity Index | 0.825 | 0.736–0.924 | 0.001 | 0.806 | 0.715–0.907 | <0.001 | |||||
Dialysis duration | 1.090 | 1.034–1.149 | 0.001 | 1.107 | 1.040–1.178 | 0.001 | |||||
Model 3 | |||||||||||
Event after KAS | 0.324 | 0.224–0.468 | <0.001 | ||||||||
Cultural factors | |||||||||||
Religious objection to LDKT | 0.642 | 0.431–0.956 | 0.029 | ||||||||
Donor preference | 0.039 | ||||||||||
No preference | 1 (reference) | 1 (reference) | 1 (reference) | ||||||||
Deceased donor | 2.484 | 1.217–5.071 | 0.012 | ||||||||
Living donor | 1.382 | 0.817–2.339 | 0.228 |
Higher value = greater amount (or higher score on) a particular variable.
Main event = received a deceased donor transplant, competing event = received a living donor transplant, died or transplant at a non-VA center, censoring = still on waitlist or other removal.
Other pairwise comparisons: black to Hispanic P = 0.123, black to other P = 0.432, Hispanic to other P = 0.612.
Other pairwise comparisons: black to Hispanic P = 0.383, black to other P = 0.702, Hispanic to other P = 0.741.
Other pairwise comparisons: black to Hispanic P = 0.578, black to other P = 0.532, Hispanic to other P = 0.328.
Other pairwise comparisons: site B to site C P < 0.001, site B to site D P = 0.283, site C to D P = 0.001.
Other pairwise comparisons: site B to site C P = 0.007, site B to site D P = 0.594, site C to D P = 0.019.
CI, confidence interval; DDKT, deceased donor kidney transplantation; KAS, Kidney Allocation System; LDKT, living donor kidney transplantation; NS, nonsignificant; SHR, subdistribution hazard ratio; VA, Veterans Affairs.