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. 2019 Dec 30;6(1):e03031. doi: 10.1016/j.heliyon.2019.e03031

Figure 4.

Figure 4

Effect of IL-1β or TGFβ1 alone or in combination on the mRNA expression of CTGF and αSMA in CFs. Quiesced cells were stimulated with IL-1β, TGFβ1 or IL-1β plus TGFβ1 (all at 10 ng/mL) for 24 h. Cells maintained in 0.5% FBS media were used as a control. mRNA levels of (A) CTGF or (B) αSMA was examined. Data represented as relative quantification (RQ) ± rqmax normalised to UBC (n=3). *P < 0.05, ***P < 0.001 vs. control; #P < 0.05, ###P < 0.001 vs. TGFβ1 (one-way repeated measures ANOVA with Tukey's multiple comparison test).