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. 2020 Jan 8;7(1):2070006. doi: 10.1002/advs.202070006

Antibacterial Biomaterials: Nonleaching Antibacterial Concept Demonstrated by In Situ Construction of 2D Nanoflakes on Magnesium (Adv. Sci. 1/2020)

Guomin Wang 1, Wenjuan Jiang 2, Shi Mo 1, Lingxia Xie 3, Qing Liao 3, Liangsheng Hu 4, Qingdong Ruan 1, Kaiwei Tang 1, Babak Mehrjou 1, Mengting Liu 5, Liping Tong 3, Huaiyu Wang 3, Jie Zhuang 6, Guosong Wu 7, Paul K Chu 1
PMCID: PMC6947495

Abstract

In article number https://doi.org/10.1002/advs.201902089, Huaiyu Wang, Jie Zhuang, Guosong Wu, Paul K. Chu, and co‐workers demonstrate a non‐leaching antibacterial concept on nanoflakes. The nanoflakes stretch bacteria on contact and the mechanical stress imposed triggers a series of reactions such as membrane rupture and reactive oxygen species burst leading to bacteria death. Biomaterials with the non‐leaching antibacterial ability are very promising in implants and cause little side effects and inflammation in vivo.

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Keywords: antibacterial, magnesium, nanoflake, nonleaching


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