To the Editor I read with interest the article by Sato et al. describing a patient with CD4(+) lymphocytopenia and disseminated cryptococcosis (1). This article does not mention whether or not HIV coinfection was present in their patient. HIV infection causes CD4(+) lymphocytopenia and cryptococcosis (2), and the treatment strategies for cryptococcosis differ between patients with and without HIV infection (2).
The author states that he has no Conflict of Interest (COI).
References
- 1. Sato S, Kambe E, Tamai Y. Disseminated cryptococcosis in a patient with multiple myeloma treated with daratumumab, lenalidomide, and dexamethasone. Intern Med 58: 843-847, 2019. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2. Perfect JR, Dismukes WE, Dromer F, et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America. Clin Infect Dis 50: 291-322, 2010. [DOI] [PMC free article] [PubMed] [Google Scholar]