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. 2019 Dec 16;11(12):1160. doi: 10.3390/v11121160

Figure 4.

Figure 4

IFI16 enhances PRRSV-induced production of IFN-β. (A) MARC-145 cells were transfected with IFI16-Myc or control vector and IFN-β reporter plasmid, and 24 h later, the cells were infected with PRRSV-2 BJ-4 at a MOI of 1 for 12 h or 24 h, and then the luciferase activities were assayed. (B) MARC-145 cells were transfected with IFI16-Myc or control vector for 24 h, then infected with PRRSV-2 BJ-4 at a MOI of 1 for 12 h or 24 h, and the mRNA levels of IFN-β were measured by RT-qPCR. All experiments were repeated at least three times with similar results. * p < 0.05, ** p < 0.01.