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. 2020 Jan 8;9:e49998. doi: 10.7554/eLife.49998

Figure 3. Changes in gene expression during conversion of monocytes into colonic or ileal macrophages.

Figure 3.

(A) Example genes that are significantly up-regulated in intestinal macrophages from monocytes to day 4: either up-regulated in the colon but do not change in the ileum, or significantly up-regulated in the ileum but do not change in the colon. Numbers indicate number of genes to follow the trend. Only genes which have significantly different levels between colonic and ileal macrophages at all time points (monocytes > day 4, day4 > day8, day8 > day12) were selected. (B) Example genes that are significantly down-regulated from monocytes to day four in intestinal macrophages: either down-regulated in the colon but do not change in the ileum, or significantly down-regulated in the ileum but do not change in the colon. Numbers indicate number of genes to follow the trend. (C) Example genes that are either up-regulated in the colon from monocytes to day four and down-regulated in the ileum from monocytes to day four or vice versa.