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The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2020 Jan 3;295(1):297. doi: 10.1074/jbc.W119.012142

Withdrawal: HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling.

Vikram D Kekatpure, Andrew J Dannenberg, Kotha Subbaramaiah
PMCID: PMC6952616  PMID: 31900379

VOLUME 284 (2009) PAGES 7436–7445

This article has been withdrawn by the authors. The actin immunoblots in Fig. 2, A and B, are the same. Lanes 4 and 6 of the CYP1A1 and CYP1B1 panels in Fig. 3B are the same. Also in Fig. 3B, lanes 2 and 4 of the 18S rRNA panel are the same. The Hsp90 lanes are all the same in Fig. 6F. The control lanes in Fig. 6H were all reused in the control siRNA lanes. Additionally, the TSA lane for Hsp90 in Fig. 6H was reused in the HDAC6 siRNA lane. The first lane of the IP: Hsp90, IB: HDAC6 lane in Fig. 6I was reused in the TSA lane for Hsp90. The first lane in the input panel in Fig. 8F was reused in Fig. 8G. Additionally, lanes 2 and 3 of the input panel in Fig. 8G are duplicated. Lane 2 of the AhR panel in Fig. 8E was reused in the actin panel in Fig. 9D and in Subbaramaiah, K., et al. (2008) J. Biol Chem. 283, 33955–33968. In Fig. 9B, lanes 2 and 3 of the input are the same. Part of the input panel in Fig. 9C was reused in Subbaramaiah, K., et al. (2008) J. Biol. Chem. 283, 33955–33968. Parts of the actin panel in Fig. 9D were reused in Subbaramaiah, K., et al. (2008) J. Biol. Chem. 283, 33955–33968. The lanes in the p23 panel of Fig. S1A are the same. In Fig. S1B, lanes 3 and 4 of the Hsp90 panel are the same as well as lanes 1 and 2 of the AhR panel, lanes 1 and 2 of the actin panel, and lanes 3 and 4 of the actin panel. In Fig. S1C, the lanes in the XAP-2 panel are the same. In Fig. S1E, the first lane of the Hsp90 panel were reused in lanes 1 and 2 of the HDAC6 panel. Also in Fig. S1E, lane 3 of the Hsp90 panel was reused in lane 3 of the XAP-2 panel. In Fig. S2, the first lane of the Hsp90 panel was reused in lanes 4 and 6 of the same panel as well as in lane 4 of the IP: Hsp90, IB: AcK panel. Also in Fig. S2, the third lane of the Hsp90 panel was reused in lane 5 of the same panel as well as lane 6 of the IP: Hsp90, IB: AcK panel. Additionally, some portions of the IP: Hsp90, IB: AcK panel were reused in Subbaramaiah, K. et al. (2008) J. Biol. Chem. 283, 33955–33968.


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