Figure 1.

Schematic representations of mechanisms of interactions between tumor cells and tumor-associated macrophages (TAMs) in leukemia (A), lymphoma (B) and myeloma (C). BMP4, bone morphogenetic protein 4; HGF, hepatocyte growth factor; NAMPT, nicotinamide phosphoribosyltransferase; HMGB1, high mobility group box 1; IDO, indoleamine 2,3-dioxygenase; Arg-1, arginase-1; VEGF, vascular endothelial growth factor; PSGL-1, P-selectin glycoprotein ligand-1; ICAM-1, intercellular adhesion molecular-1; Gfi1, growth factor independent 1; Irf7, interferon regulatory factor 7; Stat, signal transducer and activator of transcription; CSF1R, colony stimulating factor 1 receptor.