Correction to: Journal of Neurology 10.1007/s00415-019-09580-x
The original version of this article unfortunately contained a mistake. The numbers in the Table 5 appear to have been reproduced wrongly as dates, rather than percentages.
The corrected Table 5 is given in the next page.
Table 5.
Longitudinal radiological changes in relative T2-signal in MND patients
Muscle | Mean % change in relative T2-signal between baseline and 4 months (95% CI) | P value | Mean % change in relative T2-signal between baseline and 12 months (95% CI) | P value | SRM | Var ratio |
---|---|---|---|---|---|---|
Tongue | − 4.8 (− 11.2, 1.5) | 0.123 | − 2.4 (− 10.2, 5.4) | 0.540 | − 0.08 | 0.66 |
Right trapezius | − 6.9 (− 19.1, 5.2) | 0.251 | 0.2 (− 14.5, 14.8) | 0.981 | 0.06 | 0.17 |
Left trapezius | − 10.9 (− 22.9, 0.9) | 0.066 | − 1.7 (− 16.1, 12.8) | 0.816 | − 0.02 | 0.17 |
Right sternocleidomastoid | − 3.7 (− 13.4, 6.0) | 0.443 | 0.3 (− 11.5, 12.2) | 0.949 | 0.10 | 0.43 |
Left sternocleidomastoid | − 4.4 (− 14.5, 5.6) | 0.376 | − 4.1 (− 16.3, 8.2) | 0.502 | − 0.11 | 0.37 |
Splenius capitis | 4.2 (− 4.3, 12.8) | 0.321 | − 5.4 (− 16.0, 5.1) | 0.297 | − 0.42 | 0.47 |
Right deltoid | 2.7 (− 5.0, 10.4) | 0.486 | − 4.8 (− 14.4, 4.7) | 0.304 | − 0.27 | 0.71 |
Left deltoid | 1.9 (− 6.6, 10.4) | 0.654 | 4.6 (− 5.8, 15.2) | 0.365 | 0.08 | 0.59 |
Right biceps brachii | − 2.2 (− 13.8, 9.4) | 0.700 | 11.3 (− 2.9, 25.7) | 0.107 | 0.18 | 0.55 |
Left biceps brachii | − 3.5 (− 17.4, 10.1) | 0.597 | − 1.9 (− 18.6, 14.7) | 0.814 | − 0.21 | 0.26 |
Right triceps | − 13.9 (− 47.2, 18.0) | 0.378 | − 22.3 (− 65.1, 18.4) | 0.266 | − 0.19 | 0.10 |
Left triceps | − 0.0 (− 31.3, 31.2) | 0.998 | − 0.0 (− 22.1, 22.1) | 0.708 | − 0.18 | 0.00 |
Right brachioradialis | 7.3 (− 15.0, 29.9) | 0.507 | 10.4 (− 15.4, 36.8) | 0.414 | 0.04 | 0.06 |
Left brachioradialis | 7.0 (− 16.8, 31.2) | 0.551 | 9.9 (− 19.3, 39.6) | 0.492 | 0.82 | 0.23 |
Right first dorsal interosseous | 18.4 (− 1.8, 39.8) | 0.067 | 31.1 (6.8, 57.4) | 0.010 | 0.64 | 0.43 |
Left first dorsal interosseous | − 0.0 (− 26.2, 24.6) | 0.952 | 16.1 (− 16.2, 50.4) | 0.311 | 0.97 | 0.41 |
Right thenar | 14.4 (− 7.1, 36.6) | 0.177 | 21.4 (− 4.9, 48.9) | 0.100 | 0.76 | 0.26 |
Left thenar | − 8.7 (− 42.1, 23.8) | 0.586 | − 10.0 (− 50.1, 29.8) | 0.607 | − 0.57 | 0.17 |
Right hypothenar | 5.5 (− 10.6, 22.0) | 0.491 | 13.8 (− 5.8, 34.4) | 0.155 | 0.27 | 0.73 |
Left hypothenar | 3.1 (− 12.6, 18.8) | 0.691 | 2.3 (− 16.2, 20.9) | 0.802 | 0.22 | 0.34 |
Right thoracic paraspinal | − 1.0 (− 4.4, 2.4) | 0.903 | 16.7 (− 3.0, 37.6) | 0.087 | 0.30 | 0.69 |
Left thoracic paraspinal | 1.6 (− 12.1, 15.5) | 0.811 | 4.2 (− 12.7, 21.4) | 0.610 | 0.24 | 0.70 |
Right psoas | 6.2 (− 19.9, 33.1) | 0.627 | 35.7 (4.6, 71.1) | 0.020 | 0.53 | 0.52 |
Left psoas | − 11.8 (− 42.8, 17.9) | 0.419 | − 15.7 (− 54.1, 20.9) | 0.382 | − 0.01 | 0.31 |
Right gluteus maximus | − 3.0 (− 24.3, 18.1) | 0.774 | 22.0 (− 3.1, 48.8) | 0.076 | 0.44 | 0.49 |
Left gluteus maximus | − 14.2 (− 42.3, 12.2) | 0.277 | − 14.8 (− 49.8, 18.4) | 0.363 | − 0.10 | 0.53 |
Right quadriceps | 5.4 (− 2.5, 13.6) | 0.168 | 18.8 (9.0, 29.6) | < 0.001* | 0.86 | 0.90 |
Left quadriceps | 1.2 (− 7.4, 9.7) | 0.784 | 11.4 (2.9, 20.6) | 0.028 | 0.39 | 0.91 |
Right hamstrings | − 2.2 (− 10.2, 5.6) | 0.564 | 17.4 (7.7, 28.2) | < 0.001* | 0.98 | 0.93 |
Left hamstrings | 1.9 (− 7.1, 11.0) | 0.666 | 14.4 (3.3, 26.3) | 0.008* | 0.65 | 0.89 |
Right tibialis anterior | 10.7 (0.8, 21.2) | 0.030 | 28.5 (15.9, 42.7) | < 0.001* | 0.82 | 0.87 |
Left tibialis anterior | 4.1 (− 7.9, 16.5) | 0.180 | 20.9 (6.0, 37.2) | 0.004* | 0.33 | 0.86 |
Right gastrocnemius/soleus | 5.6 (− 3.2, 14.7) | 0.200 | 18.9 (8.0, 30.6) | < 0.001* | 0.64 | 0.83 |
Left gastrocnemius/soleus | 0.5 (− 8.2, 9.1) | 0.911 | 18.7 (8.0, 30.3) | < 0.001* | 0.78 | 0.88 |
Muscle-of-onset | − 0.08 (− 16.1, 16.0) | 0.698 | 16.6 (− 2.9, 37.3) | 0.070 | 0.77 | 0.73 |
Region-of-onset | 2.7 (− 4.3, 9.7) | 0.437 | 14.1 (5.5, 23.2) | 0.001* | 0.87 | 0.89 |
Summary mean | − 0.1 (− 6.2, 5.9) | 0.972 | 8.8 (1.3, 16.4) | 0.017 | 0.36 | 0.56 |
Significant T2-weighted radiological changes in MND patients between baseline and subsequent 4 and 12 month time-points are highlighted in bold. Results surviving multiple comparisons correction are asterisked
CI confidence interval, SRM standardized response mean, Var variance