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. 2019 Dec 4;11(12):653. doi: 10.3390/pharmaceutics11120653

Figure 7.

Figure 7

The effect of increasing cholesterol content and PEG-lipid in liposomes manufactured using microfluidics and different solvents. (A) Cholesterol was increased from 11 to 33 wt% in DSPC:Chol liposomes and (B) PEG-lipid content was increased from 0 to 25% within DSPC:Chol:PEG2k liposomes. Liposomes were prepared at a FRR of 3:1 and TFR of 15 mL/min for DSPC:Chol liposomes and 12 mL/min for DSPC:Chol:DSPE-PEG2k liposomes. Initial lipid concentration for both formulations was 4 mg/mL. Results represent mean ± SD from three independent batches.