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. 2019 Dec 28;11(1):57–67. doi: 10.1080/21505594.2019.1708052

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Effect of mvaT mvaU knockouts on the phenotype of P. aeruginosa PAO1. A: Percent survival of mice infected by PAO1 wild type and mvaT mvaU knockout mutants (n = 10), ***P< 0.001 via log-rank test. PAO1: 6.5 × 10³ CFU/mice; PAO1ΔT: 4 × 10³ CFU/mice; PAO1ΔU: 6.5 × 10³ CFU/mice; PAO1ΔTΔU:1.5 × 10⁴ CFU/mice. B: Biofilm formation of PAO1 wild type and mvaT mvaU knockout mutants, calculated with one-way ANOVA and Bonferroni’s multiple comparisons (n = 6), *P< 0.05, ***P< 0.001, ****P< 0.0001. C: Relative growth of the mvaT mvaU knockout mutants in comparison to PAO1, calculated with one-way ANOVA and Bonferroni’s multiple comparisons (n = 4), ***P< 0.001.