Skip to main content
. 2019 Dec 28;11(1):57–67. doi: 10.1080/21505594.2019.1708052

Table 2.

List of selected genes whose transcriptions were affected by mvaT mvaU mutations.

Gene role and gene ID Gene name log2Fold Change
 Description
PAO1ΔT Deviation value PAO1ΔU Deviation value PAO1ΔTΔU Deviation value
Pyocyanin synthesis genes/operons                
PA4210 phzA1     1.3636 0.0254 −1.7608 0.1518 phenazine biosynthesis protein
PA1899 phzA2             phenazine biosynthesis protein
PA0051 phzH         1.5799 0.0212 phenazine-modifying protein
PA4209 phzM 1.1577 0.0429 0.96629 0.0258 −1.8647 0.1073 phenazine-specific methyltransferase
PA4217 phzS     0.99553 0.0435 −3.8853 0.3877 hypothetical protein
Quorum-sensing system genes                
PA1432 lasI         1.1403 0.0210 acyl-homoserine-lactone synthase
PA1002 phnB         −2.1815 0.0522 anthranilate synthase component II
PA1430 lasR         −0.46348 0.0214 transcriptional regulator LasR
PA1431 rsaL         −1.7046 0.1243 regulatory protein RsaL
PA3476 rhlI         −2.6876 0.0798 acyl-homoserine-lactone synthase
PA3477 rhlR         −3.305 0.0469 transcriptional regulator RhlR
PA0996 pqsA         −3.7675 0.0580 anthranilate–CoA ligase
PA0997 pqsB         −3.5969 0.0488 hypothetical protein
PA0998 pqsC         −3.6549 0.0608 hypothetical protein
PA0999 pqsD         −3.5349 0.1121 3-oxoacyl-ACP synthase
PA1000 pqsE         −3.0798 0.1166 thioesterase PqsE
PA2587 pqsH         −2.402 0.0221 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
PA1003 mvfR (pqsR)         −1.2653 0.0219 transcriptional regulator MvfR
PA2226 qsrO 2.7971 0.0456     4.5068 0.0216 hypothetical protein, regulator of QS and virulence
Other virulence factor genes                
PA3479 rhlA         −3.9933 0.0683 rhamnosyltransferase subunit A
PA3478 rhlB         −3.3193 0.0284 rhamnosyltransferase subunit B
PA1130 rhlC         −2.0056 0.0300 rhamnosyltransferase
PA3724 lasB         −5.7022 0.0764 elastase LasB
Biofilm formation                
PA2232 pslB         −1.5192 0.0215 biofilm formation protein PslB
PA2233 pslC         −1.2947 0.0231 biofilm formation protein PslC
PA2234 pslD         −1.3012 0.0229 biofilm formation protein PslD
PA2235 pslE         −1.4038 0.0215 biofilm formation protein PslE
PA2236 pslF         −1.1612 0.0229 biofilm formation protein PslF
PA2237 pslG         −0.91282 0.0237 biofilm formation protein PslG
PA2238 pslH         −1.126 0.0236 biofilm formation protein PslH
PA2239 pslI         −0.99985 0.0237 biofilm formation protein PslI
PA2240 pslJ         −0.72316 0.0233 biofilm formation protein PslJ
PA3058 pelG         0.59858 0.0357 pellicle/biofilm biosynthesis Wzx-like polysaccharide transporter PelG
PA3706 wspC         −0.47283 0.0235 biofilm formation methyltransferase WspC

log2Fold Change: log2 value of the mutant signal in comparison to PAO1 signal; log2Fold Change > 0, upregulated; log2Fold Change<0, downregulated.