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. Author manuscript; available in PMC: 2021 Jan 15.
Published in final edited form as: Virology. 2019 Nov 25;540:150–159. doi: 10.1016/j.virol.2019.11.012

Fig. 2. cGAS-STING pathway agonists fail to activate innate immune signaling in LEC4.

Fig. 2.

IFN-β mRNA was measured by RT-qPCR from BEC2 and LEC4 that were transfected with (A) 2.5μg/mL, dsDNA-EC, (B) 5 μg/mL, 2′3′ cGAMP or (C) 0.5 μg/mL, high molecular weight Poly(I:C) for 4 h. The relative amount of mRNA was normalized as in Fig. 1. Data are shown as mean ± SEM from at least 3 biological replicates. *P < 0.05; ***P < 0.001; (Student’s t-test).