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. 2020 Jan 21;20:17. doi: 10.1186/s12890-020-1051-z

Correction to: Severe but not moderate hyperoxia of newborn mice causes an emphysematous lung phenotype in adulthood without persisting oxidative stress and inflammation

Anke Kindermann 1, Leonore Binder 1, Jan Baier 2, Beate Gündel 1, Andreas Simm 1, Roland Haase 2, Babett Bartling 1,
PMCID: PMC6972007  PMID: 31964360

Correction to: BMC Pulm Med

https://doi.org/10.1186/s12890-019-0993-5

Following publication of the original article [1], the authors flagged that the article had published with an error in ‘Table 1’.

Table 1.

General parameters of PND60 mice treated with neonatal hyperoxia

Parameter N mH sH
Normoxia moderate Hyperoxia severe Hyperoxia
PND60-survival a (%) 80 68* 72
Physical status
 body weight b (g) 19.3 ± 2.80 19.4 ± 2.40 19.2 ± 2.90
 wheel-running activity c (km·d− 1) 7.32 ± 1.71 7.68 ± 2.23 7.62 ± 2.38
Blood values
 erythrocytes b (n∙103∙mm−3) 6.93 ± 1.05 8.03 ± 0.57 7.22 ± 0.91
 platelets b (n∙105∙mm−3) 1.59 ± 0.88 4.41 ± 3.83* 2.31 ± 2.11
 leukocytes b (n∙103∙mm−3) 9.78 ± 2.53 9.65 ± 3.79 9.68 ± 2.78
Lung values
 lung-to-body weight b (·10−3) 1.29 ± 0.28 1.28 ± 0.26 1.37 ± 0.28
 lung wet-to-dry weight b 8.32 ± 1.43 7.84 ± 1.66 8.80 ± 1.38
 BAL cells b, d (n·103) 52.6 ± 32.9 101 ± 59.1* 58.2 ± 40.7
 BAL protein b (μg∙ml−1) 88.9 ± 35.4 80.5 ± 36.6 96.2 ± 38.7
 BAL IgM b (ng∙ml−1) 15.1 ± 13.1 16.0 ± 9.50 18.9 ± 14.7
 BAL sRAGE b (μg∙ml−1) 5.46 ± 1.49 5.39 ± 1.65 5.94 ± 2.62

Data are means ± SD with *P < 0.05 vs. N group

an = 80 in N group, n = 50 in mH group, n = 40 in sH group

bn ≥ 28 each group

cn = 17 each group. The respiratory function is more challenged by faster than slower running speeds. As female mice run faster and reach higher running distances than male mice [20], we only studied females

dCytological investigations showed alveolar monocyte-like cells as major cell type (80%) followed by differentiated macrophages (19%), granulocytes (0.8%) and lung epithelial cells (0.2%). The relative quantity of these cell types was not altered in the mH or sH group

The error was that in the row PND60-survivala the value ‘80’ was erroneously repeated, and the special symbol (*) contained in the value ‘68*’ was erroneously repeated after the value.

Table 1 has now been corrected in the published article.

Please find the corrected Table 1 below for reference.

Reference

  • 1.Kindermann, et al. Severe but not moderate hyperoxia of newborn mice causes an emphysematous lung phenotype in adulthood without persisting oxidative stress and inflammation. BMC Pulm Med. 2019;19:245. doi: 10.1186/s12890-019-0993-5. [DOI] [PMC free article] [PubMed] [Google Scholar]

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