Abstract
OBJECTIVES: To explore the prevalence and determine the risk factors of asthma in First Nations children aged 0 to 11 years living on reserves in Canada.
METHODS: In this cross-sectional study, we considered the data collected as part of the First Nations Regional Health Survey involving 6,657 children living in 238 First Nations communities in the 10 Canadian provinces, the Northwest Territories and the Yukon.
RESULTS: The overall prevalence of asthma that has lasted or is expected to last at least six months (ever-asthma) among children living on reserves was 14.6%: a prevalence of 12.9% among 0 to 4 year olds and 15.6% among 5 to 11 year olds. The prevalence of ever-asthma was greater among boys (16.1%) than girls (13.2%). Children from homes with two or more children aged less than 11 years and those who were engaged in daily physical activities were less likely to have a report of ever-asthma. Children from high-income families and smoke-free homes were more likely to have a report of ever-asthma. The association between allergy and ever-asthma was stronger in children with low birth weight. The association between chronic ear infections and ever-asthma was stronger in girls than boys.
CONCLUSIONS: The overall prevalence of ever-asthma and factors associated with ever-asthma in First Nations children living on reserves were similar to those reported for off-reserve Aboriginal children and non-Aboriginal Canadian children.
Keywords: Asthma, children, First Nations, prevalence, risk factors
Résumé
OBJECTIFS : Explorer la prévalence et déterminer les facteurs de risque de l’asthme chez les enfants des Premières Nations de 0 à 11 ans vivant dans les réserves au Canada.
MÉTHODE : Dans cette étude transversale, nous avons examiné les données recueillies dans le cadre de l’Enquête régionale longitudinale sur la santé des Premières Nations auprès de 6 657 enfants vivant dans 238 communautés des Premières nations dans les 10 provinces canadiennes, les Territoires du Nord-Ouest et au Yukon.
RÉSULTATS : La prévalence globale d’asthme ayant duré ou devant durer au moins six mois (« asthme passé ») chez les enfants vivant dans les réserves était de 14,6 %: elle était de 12,9 % chez les 0 à 4 ans et de 15,6 % chez les 5 à 11 ans. La prévalence de l’asthme passé était plus élevée chez les garçons (16,1 %) que chez les filles (13,2 %). Les enfants des ménages comptant deux enfants ou plus de moins de 11 ans et les enfants qui faisaient de l’activité physique quotidiennement étaient moins susceptibles de déclarer de l’asthme passé. Les enfants des familles à revenu élevé et ceux vivant dans des foyers sans fumée étaient plus susceptibles de déclarer de l’asthme passé. L’association entre les allergies et l’asthme passé était plus forte chez les enfants avec insuffisance de poids à la naissance. L’association entre les otites chroniques et l’asthme passé était plus forte chez les filles que chez les garçons.
CONCLUSIONS : La prévalence globale de l’asthme passé et les facteurs associés à l’asthme passé chez les enfants des Premières Nations vivant dans les réserves étaient semblables aux résultats déclarés pour les enfants autochtones vivant hors des réserves et pour les enfants canadiens non autochtones.
Mots Clés: asthme, enfant, Premiéres Nations, prévalence, facteurs de risque
Footnotes
Acknowledgements: B. Rowe is supported by a Tier I Canada Research Chair in Evidence-based Emergency Medicine from the Canadian Institutes of Health Research through the Government of Canada (Ottawa, ON). The authors thank the First Nations Information Governance Centre for allowing their research staff to access the RHS Phase 1 database for our project and conduct the statistical analyses based on our instructions.
Funding: Research was supported by a grant from the Canadian Institutes of Health Research (AHS-93245).
Conflict of Interest: None to declare.
References
- 1.Subbarao P, Mandhane PJ, Sears MR. Asthma: Epidemiology, etiology and risk factors. CMAJ. 2009;181(9):E181–90. doi: 10.1503/cmaj.080612. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Ye M, Mandhane PJ, Senthilselvan A. Association of breastfeeding with asthma in young Aboriginal children in Canada. Can Respir J. 2012;19(6):361–66. doi: 10.1155/2012/402765. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Chang HJ, Beach J, Senthilselvan A. Prevalence and risk factors of asthma in off-reserve Aboriginal children and adults in Canada. Can Respir J. 2012;19(6):e68–74. doi: 10.1155/2012/753040. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Gao Z, Rowe BH, Majaesic C, O’Hara C, Senthilselvan A. Prevalence of asthma and risk factors for asthma-like symptoms in Aboriginal and non-Aboriginal children in the northern territories of Canada. Can Respir J. 2008;15(3):139–45. doi: 10.1155/2008/302407. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Akinbami LJ, Moorman JE, Garbe PL, Sondik EJ. Status of childhood asthma in the United States, 1980–2007. Pediatrics. 2009;123(Suppl3):S131–45. doi: 10.1542/peds.2008-2233C. [DOI] [PubMed] [Google Scholar]
- 6.Chang AB, Brown N, Toombs M, Marsh RL, Redding GJ. Lung disease in indigenous children. Paediatr Respir Rev. 2014;15(4):325–32. doi: 10.1016/j.prrv.2014.04.016. [DOI] [PubMed] [Google Scholar]
- 7.First Nations Regional Longitudinal Health Survey (RHS) 2002/03. Report on Process and Methods. Available at: http://www.fnigc.ca/sites/default/files/EN pdf/RHS_2002/rhs2002-03-report_on_process_and_methods.pdf (Accessed January 29, 2016).
- 8.First Nations Regional Longitudinal Health Survey (RHS) 2002/03. Results for Adults, Youth and Children Living in First Nations Communities. Available at: http://www.fnigc.ca/sites/default/files/ENpdf/RHS_2002/rhs2002-03-technical_report.pdf (Accessed January 29, 2016).
- 9.Statistics Canada. Aboriginal Peoples in Canada: First Nations People, Métis and Inuit. Available at: http://www.www12.statcan.gc.ca/nhs-enm/2011/as-sa/99-011-x/ 99-011-x2011001-eng.cfm (Accessed January 29, 2016).
- 10.First Nations Information Governance Centre FNIGC. First Nations Regional Health Survey (RHS) 2008/10: National Report on Adults, Youth and Children Living in First Nations Communities. Ottawa, ON: FNIGC; 2012. [Google Scholar]
- 11.de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ. 2007;85(9):660–67. doi: 10.2471/BLT.07.043497. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 12.World Health Organization. The WHO Child Growth Standards. Available at: http://www.who.int/childgrowth/en/ (Accessed January 29, 2016).
- 13.Garner R, Kohen D. Changes in the prevalence of asthma among Canadian children. Health Rep. 2008;19:45–50. [PubMed] [Google Scholar]
- 14.Schröder PC, Li J, Wong GWK, Schaub B. The rural-urban enigma of allergy: What can we learn from studies around the world? Pediatr Allergy Immunol. 2015;26(2):95–102. doi: 10.1111/pai.12341. [DOI] [PubMed] [Google Scholar]
- 15.Genuneit J. Exposure to farming environments in childhood and asthma and wheeze in rural populations: A systematic review with meta-analysis. Pediatr Allergy Immunol. 2012;23(6):509–18. doi: 10.1111/j.1399-3038.2012.01312.x. [DOI] [PubMed] [Google Scholar]
- 16.The Canadian Encyclopedia 2015. Aboriginal People Demography. Available at: http://www.thecanadianencyclopedia.ca/en/article/aboriginal-people-demography/ (Accessed January 29, 2016).
- 17.The Canadian Encyclopedia 2015. Aboriginal Reserves. Available at: http://www.thecanadianencyclopedia.ca/en/article/aboriginal-reserves/ (Accessed January 29, 2016).
- 18.Eijkemans M, Mommers M, Draaisma JM, Thijs C, Prins MH. Physical activity and asthma: A systematic review and meta-analysis. PLoS One. 2012;7(12):e50775. doi: 10.1371/journal.pone.0050775. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 19.Mitchell EA, Beasley R, Björkstén B, Crane J, García-Marcos L, Keil U. ISAAC Phase Three Study Group. The association between BMI, vigorous physical activity and television viewing and the risk of symptoms of asthma, rhinoconjunctivitis and eczema in children and adolescents: ISAAC Phase Three. Clin Exp Allergy. 2013;43(1):73–84. doi: 10.1111/cea.12024. [DOI] [PubMed] [Google Scholar]
- 20.Halterman JS, Fagnano M, Conn KM, Szilagyi PG. Do parents of urban children with persistent asthma ban smoking in their homes and cars? Ambul Pediatr. 2006;6(2):115–19. doi: 10.1016/j.ambp.2005.10.004. [DOI] [PubMed] [Google Scholar]
- 21.Karmaus W, Botezan C. Does a higher number of siblings protect against the development of allergy and asthma? A review. J Epidemiol Community Health. 2002;56(3):209–17. doi: 10.1136/jech.56.3.209. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 22.Brooks C, Pearce N, Douwes J. The hygiene hypothesis in allergy and asthma: An update. Curr Opin Allergy Clin Immunol. 2013;13(1):70–77. doi: 10.1097/ACI.0b013e32835ad0d2. [DOI] [PubMed] [Google Scholar]
- 23.Yang HJ, Qin R, Katusic S, Juhn YJ. Population-based study on association between birth weight and risk of asthma: A propensity score approach. Ann Allergy Asthma Immunol. 2013;110(1):18–23. doi: 10.1016/j.anai.2012.10.010. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 24.Eldeirawi K, Persky VW. History of ear infections and prevalence of asthma in a national sample of children aged 2 to 11 years: The Third National Health and Nutrition Examination Survey, 1988 to 1994. Chest. 2004;125(5):1685–92. doi: 10.1378/chest.125.5.1685. [DOI] [PubMed] [Google Scholar]
- 25.Heinrich J, Raghuyamshi VS. Air pollution and otitis media: A review of evidence from epidemiologic studies. Curr Allergy Asthma Rep. 2004;4(4):302–9. doi: 10.1007/s11882-004-0075-4. [DOI] [PubMed] [Google Scholar]
- 26.Postma DS. Gender differences in asthma development and progression. Gend Med. 2007;4(SupplB):S133–46. doi: 10.1016/S1550-8579(07)80054-4. [DOI] [PubMed] [Google Scholar]
- 27.Yang CL, To T, Foty RG, Stieb DM, Dell SD. Verifying a questionnaire diagnosis of asthma in children using health claims data. BMC Pulm Med. 2011;11:52. doi: 10.1186/1471-2466-11-52. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 28.Cornish RP, Henderson J, Boyd AW, Granell R, Van Staa T, Macleod J. Validating childhood asthma in an epidemiological study using linked electronic patient records. BMJ Open. 2014;4(4):e005345. doi: 10.1136/bmjopen-2014-005345. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 29.Hansen TE, Evjenth B, Holt J. Validation of a questionnaire against clinical assessment in the diagnosis of asthma in school children. J Asthma. 2015;52(3):262–67. doi: 10.3109/02770903.2014.966914. [DOI] [PubMed] [Google Scholar]
- 30.Sin DD, Sharpe HM, Cowie RL, Man SF. Alberta Strategy to Help Manage Asthma Executive Committee. Spirometric findings among school-aged First Nations children on a reserve: A pilot study. Can Respir J. 2004;11(1):45–48. doi: 10.1155/2004/427686. [DOI] [PubMed] [Google Scholar]
