Article title: Low level of exosomal long non-coding RNA HOTTIP is a prognostic biomarker in colorectal cancer
Authors: Oehme F, Krahl S, Gyorffy B, Muessle B, Rao V, Greif H, Ziegler N, Lin K, Thepkaysone M-L, Polster H, Tonn T, Schneider M, Weitz J, Baenke F, Kahlert C
Journal: RNA Biology
Bibliometrics: Volume 16, Number 10, pages 1339–1345
DOI: https://doi.org/10.1080/15476286.2019.1637697
It has been noted by the authors that the Table 1 was published with errors. These errors have now been corrected as shown below. This correction has not changed the description, interpretation, or the original conclusions of the article. The authors apologize for any inconvenience caused.
Table 1.
Univariate analysis (log-rank test) of prognostic parameters in primary colorectal cancer of cohort 1 for overall survival. Data was absent for some patients regarding parameters *Grading (n= 39 total), **Resection status (n= 47 total) and ***Neoadjuvant therapy (n=28).
| Prognostic parameters | Number of patients (n=) | Mean overall survival (months) | P-Value |
|---|---|---|---|
| Age | 0.1573 | ||
| < median | 26 | 75.35 | |
| ≥ median | 26 | 67.05 | |
| Gender | 0.9214 | ||
| Female | 19 | 68.93 | |
| Male | 33 | 72.36 | |
| Localization of the tumor | 0.1422 | ||
| Rectum | 39 | 76.45 | |
| Colon | 13 | 57.59 | |
| UICC stage | |||
| I/II | 28 | 78.69 | 0.0735 |
| III/IV | 24 | 61.67 | |
| Lymph node metastasis | |||
| negative | 30 | 79.79 | 0.0264 |
| positive | 22 | 58.55 | |
| Grading* | 0.6954 | ||
| 1/2 | 33 | 69.99 | |
| 3/4 | 6 | 62.48 | |
| Resection status** | 0.7578 | ||
| R0 | 43 | 71.71 | |
| R1 | 4 | 68.97 | |
| Neoadjuvant therapy*** | 0.5671 | ||
| Received | 25 | 73.67 | |
| Not received | 3 | 68.78 | |
| Exosomal lncRNA HOTTIP | 0.0009 | ||
| Low/intermediate expression | 39 | 47.00 | |
| High expression | 13 | 80.42 |