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Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 2010 Nov 1;101(6):442–444. doi: 10.1007/BF03403960

Developing Canada’s Research Base for Harm Reduction and Health Equity Approaches to HIV Prevention and Treatment

Jeannie Shoveller 16, Kora DeBeck 26, Julio Montaner 26,36,
PMCID: PMC6973549  PMID: 21370777

Abstract

In the area of infectious disease control, Canadian research efforts to address the HIV epidemic in Vancouver’s Downtown East Side neighbourhood have fueled the development of harm reduction and health equity perspectives worldwide. These research efforts have, in turn, reshaped the field of public health approaches to HIV prevention and control. As a result of the intensive and sustained research initiatives led by Canadian scientists Drs. Thomas Kerr and Evan Wood, the ‘HIV problem’ and public health responses to it have been radically reconceptualized–shifting from an exclusive focus on individual choice towards asking fundamental questions about our society and the structural features that put people at risk for contracting HIV. Their research on harm reduction and health equity related to HIV vulnerability and outcomes has informed and shaped: 1) the establishment of North America’s first supervised injection facility, Insite, located in Vancouver’s Downtown East Side neighbourhood; 2) dramatic changes to Vancouver’s needle exchange policies; 3) HIV treatment approaches among injection drug using populations (IDU). By drawing attention to the ways in which Canadian health care policies and programs can be restructured to better support the health of vulnerable populations, the work of Drs. Kerr and Wood represents a uniquely Canadian public health milestone.

Key words: Infectious disease transmission, HIV, drug addiction, harm reduction, injection drug use, supervised injecting facilities

Footnotes

The authors developed the case for this nomination based on a large body of scientific evidence generated by Drs. Kerr and Wood and their collaborators at the BC Centre for Excellence in HIV/AIDS as well as research collaborations undertaken elsewhere in Canada and internationally.

Acknowledgements: We thank Kelly Hsu, Deborah Graham, Tricia Collingham and Carmen Rock for their assistance.

References

  • 1.Kerr T, Wood E, Small D, Palepu A, Tyndall MW. Potential use of safer injecting facilities among injection drug users in Vancouver’s downtown eastside. CMA. 2003;169:759–63. [PMC free article] [PubMed] [Google Scholar]
  • 2.Wood E, Tyndall M, Spittal P, Li K, Kerr T, Hogg R, et al. Unsafe injection practices in a cohort of injection drug users in Vancouver: Could safer injecting rooms help? CMA. 2001;165:405–10. [PMC free article] [PubMed] [Google Scholar]
  • 3.Wood E, Kerr T, Spittal P, Small W, Tyndall M, Li K, et al. The potential public health and community impacts of safer injecting facilities: Evidence from a cohort of injection drug users. JAID. 2003;32:2–8. doi: 10.1097/00126334-200301010-00002. [DOI] [PubMed] [Google Scholar]
  • 4.Wood E, Kerr T, Montaner J, Strathdee S, Wodak A, Hankins C, et al. Rationale for evaluating North America’s first medically supervised safer-injecting facility. The Lancet Infectious Disease. 2004;4:301–6. doi: 10.1016/S1473-3099(04)01006-0. [DOI] [PubMed] [Google Scholar]
  • 5.Kerr T, Wood E, Palepu A, Wilson D, Schechter MT, Tyndall MW. Responding to an explosive HIV epidemic driven by frequent cocaine injection: Is there a role for safe injecting facilities? J Drug Ist. 2003;33:579–608. doi: 10.1177/002204260303300303. [DOI] [Google Scholar]
  • 6.Wood E, Kerr T, Lloyd-Smith E, Buchner C, Marsh DC, Montaner JS, Tyndall MW. Methodology for evaluating Insite: Canada’s first medically supervised safer injection facility for injection drug users. Harm Reduct. 2004;1:9. doi: 10.1186/1477-7517-1-9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Kerr T, Stoltz J, Tyndall M, Li K, Zhang R, Montaner J, Wood E. Impact of a medically supervised safer injection facility on community drug use patterns: A before and after study. BMJ. 2006;332:220. doi: 10.1136/bmj.332.7535.220. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Kerr T, Tyndall M, Li K, Montaner J, Wood E. Safer injection facility use and syringe sharing in injection drug users. The Lancet. 2005;366:316–18. doi: 10.1016/S0140-6736(05)66475-6. [DOI] [PubMed] [Google Scholar]
  • 9.Wood E, Tyndall M, Zhang R, Stoltz J, Lai C, Montaner J, Kerr T. Attendance at supervised injecting facilities and use of detoxification services. N Engl J Med. 2006;354:2512–14. doi: 10.1056/NEJMc052939. [DOI] [PubMed] [Google Scholar]
  • 10.Wood E, Tyndall MW, Montaner JS, Kerr T. Summary of findings from the evaluation of a pilot medically supervised safer injecting facility. CMA. 2006;175:1399–404. doi: 10.1503/cmaj.060863. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Wood E, Tyndall MW, Spittal PM, Li K, Hogg RS, Montaner JS, et al. Factors associated with persistent high-risk syringe sharing in the presence of an established needle exchange programme. AIDS. 2002;16:941–43. doi: 10.1097/00002030-200204120-00021. [DOI] [PubMed] [Google Scholar]
  • 12.Wood E, Tyndall MW, Spittal PM, Li K, Hogg RS, O’Shaughnessy MV, Schechter MT. Needle exchange and difficulty with needle access during an ongoing HIV epidemic. Int J Drug Polic. 2002;13:95–102. doi: 10.1016/S0955-3959(02)00008-7. [DOI] [Google Scholar]
  • 13.Wood E, Kerr T, Spittal PM, Small W, Tyndall MW, O’Shaughnessy MV, Schechter MT. An external evaluation of a peer-run “unsanctioned” syringe exchange program. J Urban Health. 2003;80:455–64. doi: 10.1093/jurban/jtg052. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Hayashi K, Wood E, Wiebe L, Qi J, Kerr T. An external evaluation of a peerrun outreach-based syringe exchange in Vancouver, Canada. Int J Drug Policy. 2010;21:418–21. doi: 10.1016/j.drugpo.2010.03.002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15.Wood E, Kerr T. Needle exchange and the HIV outbreak among injection drug users in Vancouver, Canada. Subst Use Misus. 2006;41:841–43. doi: 10.1080/10826080600669595. [DOI] [PubMed] [Google Scholar]
  • 16.Kerr T, Wood E. Needle exchange programs and HIV outbreak among injection drug users in Vancouver, Canada: Addressing some common misper-ceptions. Toronto, ON: Canadian HIV/AIDS Legal Network; 2005. [Google Scholar]
  • 17.Kerr T, Small W, Buchner C, Zhang R, Li K, Montaner J, Wood E. Syringe sharing and HIV incidence among injection drug users and increased access to sterile syringes. Am J Public Health. 2010;100:1449–53. doi: 10.2105/AJPH.2009.178467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Wood E, Hogg RS, Bonner S, Kerr T, Li K, Palepu A, et al. Staging for anti-retroviral therapy among HIV-infected drug users. JAM. 2004;292:1175–77. doi: 10.1001/jama.292.10.1175-b. [DOI] [PubMed] [Google Scholar]
  • 19.Wood E, Hogg RS, Kerr T, Bonner S, Strathdee SA, Palepu A, Montaner JS. Rates of inappropriate antiretroviral prescription among injection drug users. Harm Reduct J. 2007;4:2. doi: 10.1186/1477-7517-4-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Wood E, Montaner JS, Chan K, Tyndall MW, Schechter MT, Bangsberg D, et al. Socioeconomic status, access to triple therapy, and survival from HIV-disease since 1996. AIDS. 2002;16:2065–72. doi: 10.1097/00002030-200210180-00012. [DOI] [PubMed] [Google Scholar]
  • 21.Wood E, Montaner JS, Tyndall MW, Schechter MT, O’Shaughnessy MV, Hogg RS. Prevalence and correlates of untreated human immunodeficiency virus type 1 infection among persons who have died in the era of modern anti-retroviral therapy. J Infect Dis. 2003;188:1164–70. doi: 10.1086/378703. [DOI] [PubMed] [Google Scholar]
  • 22.Wood E, Schechter MT, Tyndall MW, Montaner JS, O’Shaughnessy MV, Hogg RS. Antiretroviral medication use among injection drug users: Two potential futures. AIDS. 2000;14:1229–35. doi: 10.1097/00002030-200006160-00021. [DOI] [PubMed] [Google Scholar]
  • 23.Wood E, Hogg RS, Lima VD, Kerr T, Yip B, Marshall BD, Montaner JS. Highly active antiretroviral therapy and survival in HIV-infected injection drug users. JAMS. 2008;300:550–54. doi: 10.1001/jama.300.5.550. [DOI] [PubMed] [Google Scholar]
  • 24.Wood E, Kerr T, Tyndall MW, Montaner JS. A review of barriers and facilitators of HIV treatment among injection drug users. AIDS. 2008;22:1247–56. doi: 10.1097/QAD.0b013e3282fbd1ed. [DOI] [PubMed] [Google Scholar]
  • 25.Wood E, Kerr T, Montaner J. HIV treatment, injection drug use, and illicit drug policies. The Lances. 2007;370:8–10. doi: 10.1016/S0140-6736(07)61025-3. [DOI] [PubMed] [Google Scholar]
  • 26.Wood E, Hogg RS, Kerr T, Palepu A, Zhang R, Montaner JS. Impact of accessing methadone on the time to initiating HIV treatment among antiretroviral-naive HIV-infected injection drug users. AIDS. 2005;19:837–39. doi: 10.1097/01.aids.0000168982.20456.eb. [DOI] [PubMed] [Google Scholar]
  • 27.Small W, Wood E, Betteridge G, Montaner J, Kerr T. The impact of incarceration upon adherence to HIV treatment among HIV-positive injection drug users: A qualitative study. AIDS Care. 2009;21:708–14. doi: 10.1080/09540120802511869. [DOI] [PubMed] [Google Scholar]
  • 28.Kerr T, Marshall A, Walsh J, Palepu A, Tyndall M, Montaner J, et al. Determinants of HAART discontinuation among injection drug users. AIDS Care. 2005;17:539–49. doi: 10.1080/09540120412331319778. [DOI] [PubMed] [Google Scholar]
  • 29.Kerr T, Palepu A, Barness G, Walsh J, Hogg R, Montaner J, et al. Psychosocial determinants of adherence to highly active antiretroviral therapy among injection drug users in Vancouver. Antivir Ther. 2004;:407–14. [PubMed]
  • 30.Montaner J, Lima V, Barrios R, Yip B, Wood E, Kerr T, et al. Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: A population-based study. The Lancet. 2010;376:532–39. doi: 10.1016/S0140-6736(10)60936-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 31.Ministry of Health Services. News release: B.C. to seek and treat most vulnerable HIV patients. 2010. [Google Scholar]

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