Skip to main content
Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
editorial
. 2010 Jan 1;101(1):12–14. doi: 10.1007/BF03405553

Meningococcal Serogroup C Conjugate Vaccination in Canada: How Far Have We Progressed? How Far Do We Have to Go?

Craig P White 1, Jeff Scott 1,
PMCID: PMC6973578  PMID: 20364530

Abstract

Since routine meningococcal C conjugate vaccination was introduced into Canada in 2002, there have been a large regional variation in the routine programs, changes to the timing of the infant series in some provinces, and wide differences in catch-up programs. As immunization is viewed as a provincial responsibility, less attention has been paid to determining national coverage rates and the direct and indirect effects of the widely varying provincial/territorial vaccination programs on the nation as a whole. Canada’s disjointed regional immunization campaigns leave the population at risk of disease for an extended length of time. The United Kingdom has proven that with a pro-active approach to planning, coordination, and implementation of a national immunization program, excellent long-term control of invasive meningococcal disease in a large population could be achieved in as little as one year. A summation of the current meningococcal immunization strategies used in Canada and an estimate of overall vaccine coverage of children and youth is provided.

Keywords: Immunization, meningococcal C conjugate vaccine, coverage rate, herd immunity, Canada

References

  • 1.National Advisory Committee on Immunization NACI. Enhanced Surveillance of Invasive Meningococcal Disease in Canada: 1 January, 2004, through 31 December, 2005. Can Commun Dis Rep. 2007;33(10):1–15. [PubMed] [Google Scholar]
  • 2.National Advisory Committee on Immunization NACI. Can Commun Dis Rep. 2009. Update on the Invasive Meningococcal Disease and Meningococcal Vaccine Conjugate Recommendations. [PubMed] [Google Scholar]
  • 3.Ramsay ME, Andrews NJ, Trotter CL, Kaczmarski EB, Miller E. Herd immunity from meningococcal serogroup C conjugate vaccination in England: Database analysis. BMJ. 2003;326(7385):365–66. doi: 10.1136/bmj.326.7385.365. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Miller E, Salisbury D, Ramsay M. Planning, registration, and implementation of an immunisation campaign against meningococcal serogroup C disease in the UK: A success story. Vaccine. 2001;20(Suppl1):S58–S67. doi: 10.1016/S0264-410X(01)00299-7. [DOI] [PubMed] [Google Scholar]
  • 5.DeWals P, Deceuninck G, Boulianne N, DeSerres G. Effectiveness of a mass immunization campaign using serogroup C meningococcal conjugate vaccine. JAMA. 2004;292(20):2491–94. doi: 10.1001/jama.292.20.2491. [DOI] [PubMed] [Google Scholar]
  • 6.Bettinger J, Scheifele D, LeSaux M, Halperin S, Vaudry W, Tsang R. The influence of meningococcal serogroup C conjugate vaccine in Canada. Pediatr Infect Dis J. 2008;28(3):220–24. doi: 10.1097/INF.0b013e31819040e7. [DOI] [PubMed] [Google Scholar]
  • 7.Siu T, Wrency T, Dawar M, Patrick D. The impact of routine immunization using meningococcal C conjugate vaccine on invasive meningococcal disease in British Columbia. Can J Public Health. 2008;99(5):380–82. doi: 10.1007/BF03405245. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Kinlin LM, Jamieson F, Brown E, Brown S, Rawte P, Dolman S, et al. Rapid identification of herd effects with the introduction of serogroup C meningococcal conjugate vaccine in Ontario, Canada, 2000–2006. Vaccine. 2009;27:1735–40. doi: 10.1016/j.vaccine.2009.01.026. [DOI] [PubMed] [Google Scholar]
  • 9.Stephens DS. Conquering the meningococcus. FEMS Microbiol Rev. 2007;31(1):3–14. doi: 10.1111/j.1574-6976.2006.00051.x. [DOI] [PubMed] [Google Scholar]
  • 10.British Columbia Centre for Disease Control. Two-year olds; grade six students; grade 12 students with up-to-date immunizations. Vancouver, BC: British Columbia Centre for Disease Control; 2008. [Google Scholar]
  • 11.Statistics Canada. Age and sex, 2006 counts for both sexes, for Canada, provinces and territories - 100% data. Ottawa, ON: Statistics Canada; 2007. [Google Scholar]
  • 12.Keelan J, Lazar H, Wilson K. The national immunization strategy: A model for resolving jurisdictional disputes in public health. Can J Public Health. 2008;99(5):376–79. doi: 10.1007/BF03405244. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Borrow R, Miller E. Long-term protection in children with meningococcal C conjugate vaccination: Lessons learned. Expert Rev Vaccines. 2006;5(6):851–57. doi: 10.1586/14760584.5.6.851. [DOI] [PubMed] [Google Scholar]
  • 14.DeWals P, Coudeville L, Trottier P, Chevat C, Erickson LJ, Nguyen V. Vaccinating adolescents against meningococcal disease in Canada: A cost-effectiveness analysis. Vaccine. 2007;25(29):5433–40. doi: 10.1016/j.vaccine.2007.04.071. [DOI] [PubMed] [Google Scholar]
  • 15.Trotter CL, Gay NJ, Edmunds WJ. Dynamic models of meningococcal carriage, disease, and the impact of serogroup C conjugate vaccination. Am J Epidemiol. 2005;162:89–100. doi: 10.1093/aje/kwi160. [DOI] [PubMed] [Google Scholar]

Articles from Canadian Journal of Public Health = Revue Canadienne de Santé Publique are provided here courtesy of Springer

RESOURCES