Abstract
The One Health approach investigates the complexities surrounding the interplay between the animal, human and environmental domains. Zoonotic pathogens, such as Escherichia coli (E. coli) O157, which have animal reservoirs, also have direct impact on public health. Cattle are the primary reservoir of E. coli O157, however infection with this bacterium is asymptomatic. Infected cattle appear healthy and have normal growth rates and milk production abilities. Each year, thousands of Canadians become ill following exposure to E. coli O157. To reduce this public health risk, immunization of cattle would be an effective intervention. Several models have shown that on-farm pathogen reduction programs would significantly reduce the risk of human illness.
Key words: E. coli O157, One Health, pre-harvest
Résumé
L’approche «Une seule santé » porte sur l’action réciproque complexe entre les domaines animal, humain et environnemental. Les agents pathogènes zoonotiques comme Escherichia coli (E. coli) O157, qui ont des réservoirs animaux, ont aussi un impact direct sur la santé publique. Les bovins sont le principal réservoir d’E. coli O157, mais l’infection par cette bactérie est asymptomatique. Les bovins infectés semblent en bonne santé et ont des taux de croissance et des capacités de production laitière normaux. Chaque année, des milliers de Canadiens tombent malades après avoir été exposés à E. coli O157. La vaccination des bovins serait une mesure efficace pour réduire ce risque pour la santé publique. Plusieurs modèles ont montré que les programmes de réduction des agents pathogènes dans les élevages réduiraient significativement le risque de maladie chez les humains.
Mots clés: Escherichia coli O157, Une seule santé, pré-récolte
Footnotes
Conflict of Interest: Mr. Culbert and Ms. Goebel are employees of Bioniche Life Sciences. Dr. Guilbault is a consultant and has received compensation from Bioniche Life Sciences. Dr. Smith received no compensation and does not have a conflict of interest.
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