TABLE 3.
Application of neural network model to single species data and merged species dataa
| Antimicrobial | AUC for the following species (no. of isolates): |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
E. coli (1,694) |
M. tuberculosis (3,528) |
S. enterica (658) |
S. aureus (1,236) |
E. coli, M. tuberculosis, S. enterica, and S. aureus |
||||||
| Validation data | Test data | Validation data | Test data | Validation data | Test data | Validation data | Test data | Validation data | Test data | |
| Rifampin | NA | NA | 0.94 ± 0.04 | 0.94 | NA | NA | NA | NA | 0.94 ± 0.04 | 0.95 |
| Isoniazid | NA | NA | 0.88 ± 0.04 | 0.94 | NA | NA | NA | NA | 0.93 ± 0.03 | 0.94 |
| Streptomycin | NA | NA | 0.89 ± 0.06 | 0.87 | NA | NA | NA | NA | 0.89 ± 0.06 | 0.89 |
| Ethambutol | NA | NA | 0.93 ± 0.06 | 0.87 | NA | NA | NA | NA | 0.91 ± 0.05 | 0.92 |
| Pyrazinamide | NA | NA | 0.82 ± 0.11 | 0.83 | NA | NA | NA | NA | 0.85 ± 0.04 | 0.87 |
| Ciprofloxacin | 0.99 ± 0.01 | 0.97 | 0.90 ± 0.12 | 0.97 | 0.75 ± 0.15 | 0.85 | 0.98 ± 0.01 | 0.99 | 0.98 ± 0.01 | 0.97 |
a
The results for M. tuberculosis were slightly different from the results shown in Table 2, as the output dimension was changed. NA, the result is not available.