A 42-year-old female patient, a cigarette smoker with no known medical history, was referred for emergency coronary angiography because of acute coronary syndrome (ACS). She presented with sudden-onset chest pain associated with electrocardiographic evidence of ischaemia (Fig. 1a). Her blood pressure was 90/25 mm Hg. The right radial artery pulse was non-palpable. Thus we performed transfemoral coronary angiography, which showed no evidence of atherosclerosis but a smooth-bordered ostial and mid-shaft left main coronary artery (LMCA) stenosis with dynamic compression and almost complete lumen obliteration during diastole (Fig. 1b, c; Electronic Supplementary Material, Video 1). We suspected proximal aortic dissection (AD), which was confirmed by emergency echocardiography (Electronic Supplementary Material, Video 2). Indeed, LMCA pulsation was due to retrograde extension of the aortic false lumen into the LMCA causing diastolic compression of the true coronary lumen. The patient underwent a successful AD repair with Bentall’s procedure and hemi-arch replacement and patch repair of the dissected LMCA.
Fig. 1.
a Twelve-lead electrocardiogram on admission depicting ST-segment depression and negative T wave in leads II, aVF, III and V2-V6 and ST-segment elevation in lead aVR. b Non-selective left coronary artery (LCA) angiogram (systolic frame) in the left anterior oblique (LAO) caudal projection depicting a narrowed left main coronary artery (LMCA) due to an obstructing false lumen that extended from the aorta. c Non-selective LCA angiogram in the LAO caudal projection depicting a slit-like lumen of the LMCA in diastole due to compression by the false lumen
Acute proximal AD is complicated by retrograde dissection into either or both coronary ostia in 5.7–15% of cases [1, 2]; misdiagnosis with ACS may have a fatal outcome [3]. Dynamic LMCA lumen compromise during diastole is highlighted herein as a subtle and rare angiographic finding that should alert the interventional cardiologist to possible proximal AD extending into the LMCA.
Caption Electronic Supplementary Material
Video 1 Non-selective left coronary artery angiography showing dynamic left main coronary artery lumen compromise during diastole
Video 2 Echocardiographic image. Parasternal long-axis view showing a dilated aortic root harbouring a dissection flap
Conflict of interest
A.Y. Andreou, A. Karyou and A. Argyrou declare that they have no competing interests.
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Supplementary Materials
Video 1 Non-selective left coronary artery angiography showing dynamic left main coronary artery lumen compromise during diastole
Video 2 Echocardiographic image. Parasternal long-axis view showing a dilated aortic root harbouring a dissection flap