Résumé
Objectif: Déterminer l’ampleur de la non-observance du traitement de la tuberculose active à Montréal et vérifier si elle est influencée par les caractéristiques de l’organisation du système de soins.
Méthodes: Étude rétrospective des dossiers médicaux et de santé publique de patients tuberculeux rapportés à la Direction de la Santé Publique de Montréal-Centre entre 1992 et 1995. Un patient non-observant est défini comme étant celui qui a absorbé moins de 80 % de doses totales d’antituberculeux prescrites.
Résultats: Parmi les patients pour lesquels le statut d’observance était documenté, 19,8 % étaient non-observants. Dans l’analyse univariée, vivre seul, naître dans un pays à forte prévalence de tuberculose, les effets secondaires reliés à la médication, et le suivi dans une clinique non spécialisée dans le traitement de la tuberculose étaient considérés comme des facteurs de risque de la non-observance. Dans l’analyse multivariée, chaque augmentation d’une unité d’âge (RC: 1,1; 95 % IC: 1,02-1,1) et les facteurs de risque tels que l’alcoolisme (RC: 33,8; 95 % IC: 5,8-194,4) et être séropositif au VIH (RC: 8,9; 95 % IC: 2,9-26,6) étaient indépendamment associés à la non-observance.
Conclusion: La non-observance semblait être reliée de façon préférentielle aux caractéristiques individuelles des patients plutôt qu’à celles du système de soins.
Abstract
Objective: To determine the extent of non-compliance with antituberculosis treatment in Montreal and whether it is influenced by the characteristics of the health care setting.
Methods: Retrospective medical and public health chart review of tuberculosis patients reported to the Montreal-Centre Department of Public Health between 1992–1995. A non-compliant patient is defined as one who has taken less than 80% of prescribed antituberculosis medication.
Results: Among patients for whom the compliance status was available, 19.8% were noncompliant. In univariate analysis, risk factors significantly associated with non-compliance included: living alone, birth in an endemic country for tuberculosis, side effects related to the medication, and follow-up in a clinic not specialized for tuberculosis. In multivariate analysis, increase of age by one unit (OR: 1.1; 95% CI: 1.02-1.1), and risk factors such as alcoholism (OR: 33.8; 95% CI: 5.8-194.4) and being HIV positive (OR: 8.9; 95% CI: 2.9-26.6) were independently associated with non-compliance.
Conclusion: Non-observance seemed to be associated with patients’ characteristics rather than health care system characteristics.
Footnotes
Cet article a été réalisé dans le cadre de sa Maîtrise en Santé Communautaire à l’Université de Montréal. RÉFÉRENCES
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