Skip to main content
Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 1999 Nov 1;90(6):385–388. doi: 10.1007/BF03404140

Geographic Origin and Risk for Congenital Infection in a Canadian Inner City: Findings and Implications for Policy

David W Grossman 17,27,, Laura M Hans 37, Richard Glazier 27,47
PMCID: PMC6979868  PMID: 10680261

Abstract

This study examines associations between geographic origin and risk for congenital infections, through a chart review of women from the St. James Town area of Toronto delivering at Wellesley Hospital in 1996. Foreign-born women (n=203) were significantly less likely than Canadian-born women (n=53) to be HBsAg negative (187/193 vs. 48/48; RR=0.97, 95%CI 0.94–0.99). There was no significant difference in rubella seronegativity, but rubella immunity was unacceptably low in both groups (less than 90%). A number of rubella non-immune women had delivered previously in Canada. Procedures must be implemented to ensure completion of hepatitis B immunization series in affected newborns, and rubella immunization in seronegative women prior to discharge. As well, updating immunization status must become a routine part of the immigration medical examination.

Footnotes

The first two authors listed should be considered jointly as “first author”. This research was conducted while these authors were completing the requirements of the Family Medicine Residency Program at the Wellesley Central Hospital, University of Toronto

Funded in part by a grant from the Bureau of Reproductive and Child Health, Health Canada

References

  • 1.Society of ObstetriciansGynaecologists of Canada. Healthy Beginnings: Guidelines for Care During Pregnancy and Childbirth. SOGC Home Page [Internet Document] 1994. [Google Scholar]
  • 2.Laboratory Centre for Disease Control LCDC Expert Working Group on Canadian Guidelines for Sexually Transmitted Diseases. Canadian STD Guidelines. Ottawa: Health Canada; 1998. [Google Scholar]
  • 3.Ford-Jones EL. Congenital and perinatal infection in a culturally diverse population. Toronto: St. Joseph’s Hospital; 1995. [Google Scholar]
  • 4.Sundquist J. Migration and: Epidemiological Studies in Swedish Primary Health Care [Dissertation] Lund: Sigillum Universitatis Gothorum Carolinae; 1994. [Google Scholar]
  • 5.World Health Organization, UNICEF. State of the World’s Vaccines and Immunization. 1996. [Google Scholar]
  • 6.Robertson SE, Cutts FT, Samuel R, Diaz-Ortega J-L. Control of rubella and congenital rubella syndrome (CRS) in developing countries, part 2: Vaccination against rubella. Bull World Health Organ. 1997;75(1):69–80. [PMC free article] [PubMed] [Google Scholar]
  • 7.Ford-Jones EL. January. 1996. Protocol for the evaluation of infectious diseases in pregnant immigrant and refugee women and their infants. Hospital for Sick Children, Toronto [Research Proposal] p. 5. [Google Scholar]
  • 8.Gyorkos TW, Tannenbaum TN, Abrahamowicz N, et al. Rubella screening and vaccination of pregnant women: Report card 1993–4. Canadian National Immunization Conference. Toronto, Canada; December 8–11, 1996.
  • 9.Franks AL, Berg CJ, Kane MA, et al. Hepatitis B virus infection among children born in the United States to Southeast Asian refugees. N Engl J Med. 1989;321(19):1301–5. doi: 10.1056/NEJM198911093211905. [DOI] [PubMed] [Google Scholar]
  • 10.Hurie MB, Gennis MA, Hernandez LV, et al. Prevalence of hepatitis B markers and measles, mumps, and rubella antibodies among Jewish refugees from the former Soviet Union. JAMA. 1995;273(12):954–56. doi: 10.1001/jama.1995.03520360068041. [DOI] [PubMed] [Google Scholar]
  • 11.Duclos P, Tepper ML, Weber J, Marusyk RG. Seroprevalence of measles- and rubella-specific antibodies among military recruits, Canada, 1991. Can J Public Health. 1994;85(4):278–81. [PubMed] [Google Scholar]
  • 12.Canadian Task Force on the Periodic Health Examination. Clinical Preventive Health Care. Ottawa: Canada Communications Group; 1994. [Google Scholar]
  • 13.Pelletier L, Duclos P. Surveillance of congenital rubella syndrome and other rubella-associated adverse pregnancy outcomes. Can Commun Dis Rep. 1996;22(5):35–37. [PubMed] [Google Scholar]
  • 14.Glazier R, Badley E, Arnold J. Sociodemographic Profiles. Toronto: Southeast Toronto Health Profiles Project; 1994. [Google Scholar]
  • 15.Statistics Canada. Postal Code Census File. 1991. [Google Scholar]
  • 16.SPSS for Windows. 8.0.2 ed. SPSS Inc., 1998.
  • 17.Murray CJL, Lopez AD. Global Health Statistics: A Compendium of Incidence, Prevalence and Mortality Estimates for Over 200 Conditions. Harvard School of Public Health on behalf of WHO and the World Bank, 1996. Global Burden of Disease and Injury Series; vol II.
  • 18.CitizenshipImmigration Canada. Medical Report for Canadian Immigration. 1994. [Google Scholar]
  • 19.Maynard JE, Hepatitis B. Global importance and need for control. Vaccine. 1990;8(Supplement):S18–S20. doi: 10.1016/0264-410X(90)90209-5. [DOI] [PubMed] [Google Scholar]
  • 20.Hollinger FB, Group NARS. Controlling hepatitis B virus transmission in North America. Vaccine. 1990;8(Supplement):S122–S128. doi: 10.1016/0264-410X(90)90232-B. [DOI] [PubMed] [Google Scholar]
  • 21.World Health Organization. Expanded Programme on Immunization (EPI) 1997. [Google Scholar]
  • 22.Cutts FT, Robertson FE, Diaz-Ortega J-L, Samuel R. Control of rubella and congenital rubella syndrome (CRD) in developing countries, part 1: Burden of disease from CRS. Bull World Health Organ. 1997;75(1):55–68. [PMC free article] [PubMed] [Google Scholar]
  • 23.Anonymous. Mumps and rubella consensus conference. Can Commun Dis Rep. 1994;20(19):165–76. [PubMed] [Google Scholar]
  • 24.Gyorkos TW, Tannenbaum TN, Abrahamowicz M, et al. Evaluation of rubella screening in pregnant women. CMAJ. 1998;159(9):1091–97. [PMC free article] [PubMed] [Google Scholar]

Articles from Canadian Journal of Public Health = Revue Canadienne de Santé Publique are provided here courtesy of Springer

RESOURCES