Skip to main content
Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 2002 May 1;93(3):203–207. doi: 10.1007/BF03405001

Impact of Maternal Anemia on the Infant’s Iron Status at 9 Months of Age

Nadya Savoie 1, France M Rioux 1,
PMCID: PMC6980000  PMID: 12050988

Abstract

Background: Iron-deficiency anemia during pregnancy is still common in developed countries. The aim of this study was to evaluate the influence of maternal anemia on the infant’s iron status at 9 months of age in Moncton, NB.

Methods: Mothers giving birth between April 1998 and February 1999 were selected from medical records. A letter was sent to invite them to participate. In total, 75 mothers with their infants were examined.

Results: The proportion of iron-deficiency anemia was higher (p = 0.055) in the group born to anemic compared to non-anemic mothers. A positive association between the mother’s haemoglobin and haematocrit during her 3rd trimester and her infant’s haemoglobin and haematocrit was found at 9 months of age. These results are not explained by differences in feeding practices and socio-economic status between groups.

Interpretation: Infants born to mildly anemic mothers may be at risk of developing anemia.

References

  • 1.Gaspar MJ, Ortega RM, Moreiras O. Relationship between iron status in pregnant women and their newborn babies. Acta Obstet Gynecal Scand. 1993;72:534–37. doi: 10.3109/00016349309058158. [DOI] [PubMed] [Google Scholar]
  • 2.Allen LH. Pregnancy and iron deficiency: Unresolved issues. Nutr Rev. 1997;55(4):91–101. doi: 10.1111/j.1753-4887.1997.tb06460.x. [DOI] [PubMed] [Google Scholar]
  • 3.Lozoff B, Jimenez E, Wolf AW. Long-term developmental outcome of infants with iron deficiency. N Engl J Med. 1991;325:687–94. doi: 10.1056/NEJM199109053251004. [DOI] [PubMed] [Google Scholar]
  • 4.Walter T, de Andraca I, Chadud P, Perales CG. Iron deficiency anemia: Adverse effects on infant psychomotor development. Paediatrics. 1989;84:7–17. [PubMed] [Google Scholar]
  • 5.de Andraca I, Castillo M, Walter T. Psychomotor development and behavior in iron-deficient anemic infants. Nutr Rev. 1997;55:125–32. doi: 10.1111/j.1753-4887.1997.tb06463.x. [DOI] [PubMed] [Google Scholar]
  • 6.Kwik-Urbe CL, Golubt MS, Keen CL. Behavioral consequences of marginal iron deficiency during development in a murine model. Neurotoxicol Teratol. 1999;21:661–72. doi: 10.1016/S0892-0362(99)00041-0. [DOI] [PubMed] [Google Scholar]
  • 7.Feightner JW. Canadian Guide to Clinical Preventive Health Care. Ottawa: Health Canada; 1994. Prevention of iron deficiency anemia in infants. In: Canadian Task Force on the Periodic Health Examination; pp. 244–55. [Google Scholar]
  • 8.Société C d p l d d C e S Canada. Nutrition du nourrisson en santé né à terme. Ministre de travaux publics et Services gouvernementaux du Canada. 1998. [Google Scholar]
  • 9.Singla PN, Tyagi M, Kumar A, Dash D, Shankar R. Fetal growth in maternal anemia. J Trop Pediatr. 1997;43:89–92. doi: 10.1093/tropej/43.2.89. [DOI] [PubMed] [Google Scholar]
  • 10.Hokama T, Takenaka S, Hirayama K, Yara A, Yoshida K, Itokazu K, et al. Iron status of new-borns born to iron deficient anemic mothers. J Trop Pediatr. 1996;42:75–77. doi: 10.1093/tropej/42.2.75. [DOI] [PubMed] [Google Scholar]
  • 11.Bhargava M, Iyer PU, Kumar R, Ramji A, Kapani V, Bhargava K. Relationship of maternal serum ferritin with foetal serum ferritin, birth weight and gestation. J Trop Pediatr. 1991;37:149–52. doi: 10.1093/tropej/37.4.149. [DOI] [PubMed] [Google Scholar]
  • 12.Choi JW, Kim CS, Pai SH. Erythropoietic activity and soluble transferring receptor level in neonates and maternal blood. Acta Paediatr. 2000;89:675–79. doi: 10.1111/j.1651-2227.2000.tb00363.x. [DOI] [PubMed] [Google Scholar]
  • 13.Colomer J, Colomer C, Gutierrez D, Jubert A, Nolasco A, Donat J, et al. Anaemia during pregnancy as a risk factor for infant iron deficiency: Report from the Valencia Infant Anaemia Cohort (VIAC) Study. Paediatr Perinat Epidemiol. 1990;4:196–204. doi: 10.1111/j.1365-3016.1990.tb00638.x. [DOI] [PubMed] [Google Scholar]
  • 14.Kilbride J, Baker TG, Parapia LA, Khoury SA, Shuqaidef SW, Jerwood D. Anaemia during pregnancy as a risk factor for iron-deficiency anaemia in infancy: A case-control study in Jordan. Int J Epidemiol. 1999;28:461–68. doi: 10.1093/ije/28.3.461. [DOI] [PubMed] [Google Scholar]
  • 15.Piwoz EG, Creed de Kanashiro H, Lopez de Romana G, Black RE, Brown KH. Potential for misclassification of infants’ usual feeding practices using 24-hour dietary assessment methods. J Nutr. 1995;125(1):57–65. doi: 10.1093/jn/125.1.57. [DOI] [PubMed] [Google Scholar]
  • 16.Rioux MF, Michaud J. Anémie maternelle dans les régions du sud-est et nord-est du Nouveau-Brunswick et impact sur les paramètres hématologiques et la croissance du nouveau-né. Can J Diet Prac Res. 2001;62:70–75. [PubMed] [Google Scholar]
  • 17.Turgeon-O’Brien H, Santure M, Maziade J. The association of low and high ferritin levels and anemia with pregnancy outcome. Can J Diet Prac Res. 2000;61(3):121–27. [PubMed] [Google Scholar]
  • 18.Laverdière S, Turgeon-O’Brien H. État nutri-tionnel en fer d’un groupe d’enfants âgés de 12 à 20 mois de la région de Charlevoix du Québec. Med Nut. 1997;5:181–89. [Google Scholar]
  • 19.Lehmann F, Gray-Donald K, Mongeon M, Di Tommaso S. Iron deficiency anemia in 1-year-old children of disadvantaged families in Montreal. CMAJ. 1992;146(9):1571–77. [PMC free article] [PubMed] [Google Scholar]
  • 20.Innis SM, Nelson CM, Wadsworth LD, MacLaren IA, Lwanga D. Incidence of iron-deficiency anaemia and depleted iron stores among nine-month-old infants in Vancouver, Canada. Can J Public Health. 1997;88(2):80–84. doi: 10.1007/BF03403865. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Sherriff A, Emond A, Bell JC, Golding J. ALSPAC study team. Should infants be screened for anaemia? A prospective study investigating the relation between haemoglobin at 8, 12, and 18 months and development at 18 months. Arch Dis Child. 2001;84:480–85. doi: 10.1136/adc.84.6.480. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Canadian Journal of Public Health = Revue Canadienne de Santé Publique are provided here courtesy of Springer

RESOURCES