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Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 1999 Mar 1;90(2):127–132. doi: 10.1007/BF03404116

Morbidity and Mortality Related to Human Immunodeficiency Virus in Canadian Men and Women, 1987–94

Amy E Weber 113, Robert S Hogg 113,213,
PMCID: PMC6980007  PMID: 10349221

Abstract

Objective: To assess the impact of HIV/AIDS on hospitalization and mortality patterns in Canada.

Methods: Hospitalizations and deaths due to HIV/AIDS were compared with select causes of morbidity and mortality among men and women across provinces, regions and select cities between 1987–94. Patterns of hospitalization and mortality were characterized by calculating age-specific, standardized rates, rate ratios and potential years of life lost before 65 years.

Results: A total of 28,462 hospitalizations (26,153 in men and 2,309 in women) and 8,739 deaths (8,192 in men and 547 in women) were attributed to HIV/AIDS during the study period. Rates of HIV/AIDS hospitalization were highest for men in Ontario, Quebec and British Columbia, and in Montreal, Toronto and Vancouver; while among women they were highest in Quebec and in Montreal, Toronto and Vancouver. Mortality rates followed a pattern similar to the rates found for hospitalization.

Conclusions: Our analysis reveals the considerable impact of HIV/AIDS on patterns of morbidity and mortality in Canada.

Footnotes

This work was supported in part by a grant from the Bureau of HIV/AIDS and STD, Laboratory Centre for Disease Control, Health Canada and from National Health Research Development, Health Canada, and through a National Health Research Scholar Award from Health Canada to Dr. Hogg.

References

  • 1.Centers for Disease ControlPrevention Update Trends in AIDS incidence, deaths, and prevalence — United States. 1996. Morb Wkly Rep. 1997;46:165–73. [PubMed] [Google Scholar]
  • 2.Castilla J, Martínez de Aragón MV, Gutierrez A, et al. Impact of human immunodeficiency virus infection on mortality among young men and women in Spain. Int J Epidemiol. 1997;26:1346–51. doi: 10.1093/ije/26.6.1346. [DOI] [PubMed] [Google Scholar]
  • 3.Barbara JC, Mur CB, Mayans MV, et al. Premature mortality related to AIDS among men and women in Catalonia. AIDS. 1993;7:1099–103. doi: 10.1097/00002030-199308000-00012. [DOI] [PubMed] [Google Scholar]
  • 4.Conti S, Farchi G, Prati S. AIDS as a leading cause of death among young adults in Italy. Eur J Epidemiol. 1994;10:669–73. doi: 10.1007/BF01719279. [DOI] [PubMed] [Google Scholar]
  • 5.Flandre P, Valleron AJ. Impact démographique de la mortalité par SIDA en France en 1990: le SIDA devant le suicide et proche des accidents de la circulation. Rev Épidémiol Santé. 1988;36:196–201. [PubMed] [Google Scholar]
  • 6.Bindels PJE, Reijneveld SA, Mulder-Folkerts DKF, et al. Impact of AIDS on premature mortality in Amsterdam, 1982–1992. AIDS. 1994;8:233–37. doi: 10.1097/00002030-199402000-00011. [DOI] [PubMed] [Google Scholar]
  • 7.Aldous J, Hickman M, Ellam A, et al. Impact of HIV infection on mortality in young men in a London health authority. Br Med J. 1992;305:219–21. doi: 10.1136/bmj.305.6847.219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Gold J, Yueming L, Kaldor JM. Premature mortality in Australia 1983–1992, the first decade of the AIDS epidemic. Med J Australia. 1994;161:653–56. doi: 10.5694/j.1326-5377.1994.tb126910.x. [DOI] [PubMed] [Google Scholar]
  • 9.Hogg RS, Schechter MT, Montaner JSG, et al. Impact of HIV infection and AIDS on death rates in British Columbia and Canada. Can Med Assoc J. 1994;150:711–17. [PMC free article] [PubMed] [Google Scholar]
  • 10.Hogg RS, Heath KV, Strathdee SA, et al. HIV/AIDS mortality in Canada: Evidence of gender, regional and local area differentials. AIDS. 1996;10:889–94. doi: 10.1097/00002030-199607000-00012. [DOI] [PubMed] [Google Scholar]
  • 11.Age, SexMarital Status. The Nation. Ottawa: Statistics Canada; 1992. [Google Scholar]
  • 12.Postcensal Annual Estimates of Population by Marital Status, Age, Sex and Components of Growth for Canada, Provinces and Territories, June 1, 1987–1991, vol. 5–9, Demography Division, Statistics Canada, Ottawa, 1987–1991.
  • 13.Peron Y, Strohmenger C. Demographic and health indicators. Presentation and interpretation. Ottawa: Statistics Canada; 1985. [Google Scholar]
  • 14.Breslow NE, Day NE. Statistical methods in cancer research. Vol II— the design and analysis of cohort studies. Lyon: International Agency for Research on Cancer; 1987. [PubMed] [Google Scholar]
  • 15.Kozak LJ, McCarthy E, Moien M. Patterns of hospital use by patients with diagnoses related to HIV infection. Public Health Rep. 1993;108(5):571–81. [PMC free article] [PubMed] [Google Scholar]
  • 16.Rosenblum LS, Buehler JW, Morgan M, Moien M. Increasing impact of HIV infection on hospitalizations in the United States, 1983–1988. J Acquired Immune Deficiency Syndromes. 1992;5:497–504. doi: 10.1097/00126334-199205000-00011. [DOI] [PubMed] [Google Scholar]
  • 17.Fortgang IS, Moore RD. Hospital admissions of HIV-infected patients from 1988 to 1992 in Maryland. J Acquired Immune Deficiency Syndromes and Human Retroviruses. 1995;8:365. 72. [PubMed] [Google Scholar]
  • 18.Hogg RS, O’Shaughnessy MV, Gataric N, et al. Decline in AIDS due to new antiretrovirals. Lancet. 1997;349:1294. doi: 10.1016/S0140-6736(05)62505-6. [DOI] [PubMed] [Google Scholar]
  • 19.Hogg RS, Heath KV, Yip B, et al. Improved survival among HIV-infected individuals following initiation of antiretroviral therapy. JAMA. 1998;279:450–54. doi: 10.1001/jama.279.6.450. [DOI] [PubMed] [Google Scholar]
  • 20.Palella FJ, Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. NEJM. 1998;388:853–60. doi: 10.1056/NEJM199803263381301. [DOI] [PubMed] [Google Scholar]
  • 21.Brodt HR, Kamps BS, Gute P, et al. Changing incidence of AIDS-defining illnesses in the era of antiretroviral combination therapy. AIDS. 1997;11:1731–38. doi: 10.1097/00002030-199714000-00010. [DOI] [PubMed] [Google Scholar]
  • 22.Egger M, Hirschel B, Francioli P, et al. Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: Prospective multicentre study. BMJ. 1997;315:1194–99. doi: 10.1136/bmj.315.7117.1194. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Hesson NA, Buchbinder SP, Colbert D, et al. Impact of HIV infection of mortality and accuracy of AIDS reporting on death certificates. Am J Public Health. 1992;82:561–64. doi: 10.2105/AJPH.82.4.561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Johnson RJ, Montano BLK, Wallace EM. Using death certificates to estimate completeness of AIDS case reporting in Ontario in 1985–87. CMAJ. 1989;141:537–40. [PMC free article] [PubMed] [Google Scholar]
  • 25.Remis RS, Palmer RWH. Modelling AIDS mortality from survival analysis to evaluate completeness of reporting; 1991. [Google Scholar]

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