Skip to main content
Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 2002 Jul 1;93(4):259–263. doi: 10.1007/BF03405012

Pregnancy Planning: A Determinant of Folic Acid Supplements Use for the Primary Prevention of Neural Tube Defects

Pascale Morin 14,, Philippe De Wals 24, Denise St-Cyr-Tribble 34, Théophile Niyonsenga 44, Hélène Payette 54
PMCID: PMC6980095  PMID: 12154526

Abstract

Objective: Daily consumption of supplements containing 400 μg of folic acid in the periconception period may reduce the risk of neural tube defects (NTDs) by as much as 70%. However, despite explicit recommendations, folic acid consumption among women likely to become pregnant remains low. The objectives of this study were: to evaluate women’s knowledge and beliefs with regard to folic acid; to estimate the frequency of vitamin supplement consumption; and to identify its determinants during the periconception period.

Methods: In 1999–2000, a questionnaire was completed by 1,240 pregnant women in 10 Quebec hospitals.

Results: Seventy percent of the respondents were aware of the preventive role of folic acid but only 25% had taken the recommended dose of supplements during the periconception period. Supplement consumption is associated with the pregnancy planning intensity score (OR: 1.06; 95% CI: 1.02–1.11), knowledge score (OR: 1.11; 95% CI: 1.07–1.16) and belief in the usefulness of supplements (OR: 1.56; 95% CI: 1.02–2.39).

Conclusion: These results indicate that further efforts are needed to inform the population and promote the optimal use of folic acid supplements.

Footnotes

Acknowledgements: This study was funded by Kellogg Canada Inc. Pascale Morin has a scholarship from the Danone Institute of Canada.

We thank Mrs. Louise Gravel-Roy and Geneviève Anctil for collecting the data. We also thank the employees from the participating hospitals: Centre hospitalier Angrignon, Centre hospitalier Anna-Laberge, Centre hospitalier d’Asbestos, Centre hospitalier Beauce-Etchemin, Centre hospitalier Notre-Dame–du-Lac, Centre hospitalier Pierre-Boucher, Centre hospitalier universitaire de Montréal, Centre universitaire de santé de l’Estrie, Hôpital La Pocatière et Hôtel-Dieu de Lévis.

References

  • 1.Chambers K, Popkin J, Arnold W, Irwin B, Hall JG. Neural tube defects in British Columbia? Lancet. 1994;343(8895):489–90. doi: 10.1016/S0140-6736(94)92743-X. [DOI] [PubMed] [Google Scholar]
  • 2.De Wals P, Trochet C, Pinsonneault L. Prevalence of neural tube defects in the province of Quebec, 1992. Can J Public Health. 1997;90(4):237–39. doi: 10.1007/BF03404123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Crane JMG, Sun C, Hutchens D, Crowley M. The epidemiology of neural tube defects in Newfoundland and Labrador. J Soc Obstet Gynecol Can. 2001;23:510–14. [Google Scholar]
  • 4.Moore KL. L’être humain en développement. Embryologie orientée vers la clinique. Toronto: N.B. Saunders Company; 1974. [Google Scholar]
  • 5.Botto LD, Moore CA, Khoury MJ, Erickson JD. Neural tube defects. Medical Progress. 1999;341(20):1509–19. doi: 10.1056/NEJM199911113412006. [DOI] [PubMed] [Google Scholar]
  • 6.McCourt C. Primary prevention of neural tube defects (issued by the HPB) CMAJ. 1993;148(9):1451. [PMC free article] [PubMed] [Google Scholar]
  • 7.SOGC Genetics Committee. Folic acid for the prevention of neural tube defects. Pediatrics. 1993;92(3):493–94. [PubMed] [Google Scholar]
  • 8.Canadian Task Force. Periodic Health Examination, 1994 update: 3. Primary and secondary prevention of neural tube defects. CMAJ. 1994;151(2):159–66. [PMC free article] [PubMed] [Google Scholar]
  • 9.Lewis CJ, Crane NT, Wilson DB, Yetley EA. Estimated folate intakes: Data updated to reflect food fortification, increased bioavailability, and dietary supplement use. Am J Clin Nutr. 1999;70:198–207. doi: 10.1093/ajcn.70.2.198. [DOI] [PubMed] [Google Scholar]
  • 10.Raats M, Thorpe L, Hurren C, Elliott K. Changing Preconceptions. London: Health Education Authority; 1998. [Google Scholar]
  • 11.Morin P, St-Cyr-Tribble D, De Wals P, Payette H. Concept analysis of pregnancy planning drawn from women of childbearing age. Health Promotion Practice. 2001;2(3):212–21. doi: 10.1177/152483990100200305. [DOI] [Google Scholar]
  • 12.Miller WB. Personality traits and developmental experiences as antecedents of childbearing motivation? Demography. 1992;29(2):265–85. doi: 10.2307/2061731. [DOI] [PubMed] [Google Scholar]
  • 13.Morin P, Payette H, Moos MK, St-Cyr-Tribble D, Niyonsenga T, De Wals P. Pediatric and Perinatal Epidemiology. 2002. Measuring the intensity of pregnancy planning. [DOI] [PubMed] [Google Scholar]
  • 14.Pender NJ. Health Promotion in Nursing Practice. Third. Stanford, Connecticut: Appleton and Lange; 1996. [Google Scholar]
  • 15.Bonin M, Bretzlaff J, Therrien S, Rowe B. Knowledge of periconceptional folic acid for the prevention of neural tube defects. The missing links. Arch Fam Med. 1998;7:438–42. doi: 10.1001/archfami.7.5.438. [DOI] [PubMed] [Google Scholar]
  • 16.de Jong-van den B L, de Walle HEK, van der Pal-de Bruin KM, Buitendijk SE, Cornel MC. Increasing awareness of and behaviour towards periconceptional folic acid consumption in The Netherlands from 1994 to 1995. Eur Clin Pharmacol. 1998;54:329–31. doi: 10.1007/s002280050468. [DOI] [PubMed] [Google Scholar]
  • 17.McDonnell R, Johnson Z, Doyle A, Sayers G. Folic acid knowledge and use among expectant mothers in 1997: A comparison with 1996? Ir Med J. 1999;92(3):296–301. [PubMed] [Google Scholar]
  • 18.Goldstein H. Multilevel Statistical Models. Second 1995. [Google Scholar]
  • 19.Rothman KJ, Greenland S. Modern Epidemiology. Second. Philadelphia, PA: Lippincott–Raven Publishers; 1998. [Google Scholar]
  • 20.Hennekens CH, Buring JE. Epidemiology in Medicine. Toronto: Little, Brown and Company; 1987. [Google Scholar]
  • 21.Green LL, Richard L, Potvin L. Ecological foundations of health promotion. Am J Health Prom. 1996;10(4):270–81. doi: 10.4278/0890-1171-10.4.270. [DOI] [PubMed] [Google Scholar]
  • 22.Ruben BD. Communication and Human Behavior. New York: Macmillan Publishing Company; 1984. [Google Scholar]

Articles from Canadian Journal of Public Health = Revue Canadienne de Santé Publique are provided here courtesy of Springer

RESOURCES