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Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 2003 Jan 1;94(1):64–67. doi: 10.1007/BF03405055

Effectiveness and Cost Comparison of Two Strategies for Hepatitis B Vaccination of Schoolchildren

Maryse Guay 113,213,313,413,, Anne-Marie Clouâtre 113, Manon Blackburn 113,213, Geneviève Baron 113,313, Philippe De Wals 113,213,313, Chantale Roy 513, Jean Desrochers 513, François Milord 113,213
PMCID: PMC6980189  PMID: 12583682

Abstract

Context: In 1994, immunization against hepatitis B was implemented in schools in Quebec, targeting grade 4 students. In 1996–1997 and 1997–1998, one Local Community Service Centre (CLSC) replaced the school-based program in its district with vaccination offered in community clinics after school hours. The aim of the current study was to compare the effectiveness and costs of school-based and clinic-based programs.

Methods: Vaccination coverage data were collected in the CLSC with the clinic-based program (CBP), and in three matched CLSCs with a school-based program (SBP), from 1994 to 2000. Surveys were conducted to estimate costs to parents, to schools and to CLSCs in 1997–1998.

Results: With the implementation of the CBP, the vaccination coverage fell to 73%, compared with over 90% in the SBPs. Coverage increased to 90% when the CBP was abandoned. Costs to the CLSC were not much lower in the CBP. Societal costs were $63 per student vaccinated in the CBP, and ≤40 in the SBPs.

Conclusion: Results demonstrate the advantage of a SBP over a CBP for the immunization of schoolchildren.

Footnotes

Acknowledgement: This study was funded by the “Programme conjoint MSSS-RRSSS de subvention en santé publique”.

References

  • 1.Ministère de la Santé et des Services sociaux, Circulaire 1994-04-05 sur le programme de vaccination contre l’hépatite B. Québec: Direction de la protection de la santé publique, Ministère de la Santé et des Services sociaux, 1994.
  • 2.Plaitano S, Sagliocca L, Mele A, Bove C, Protano D, Adamo B, et al. Hepatitis B mass immunization of adolescents: A pilot study in a community. Eur J Epidemiol. 1993;9(3):307–10. doi: 10.1007/BF00146268. [DOI] [PubMed] [Google Scholar]
  • 3.Centers for Disease ControlPrevention. Hepatitis B vaccination of adolescents — California, Louisiana and Oregon, 1992-1994. MMWR. 1994;43:605–9. [PubMed] [Google Scholar]
  • 4.Poulin C, Duval B, Alary M, Ringuet J, Pelletier G, Bouchard A. Étude de faisabilité de l’application d’un programme de vaccination contre l’hépatite B chez les adolescents en milieu scolaire. Québec: Ministère de la Santé et des Services sociaux; 1994. [Google Scholar]
  • 5.Cassidy WM, Mahoney FJ. A hepatitis B vaccination program targeting adolescents. J Adolesc Health. 1995;17(4):244–47. doi: 10.1016/1054-139X(95)00132-C. [DOI] [PubMed] [Google Scholar]
  • 6.Dobson S, Scheifele D, Bell A. Assessment of a universal, school-based hepatitis B vaccination program. JAMA. 1995;274(15):1209–13. doi: 10.1001/jama.1995.03530150033030. [DOI] [PubMed] [Google Scholar]
  • 7.Stewart P, MacDonald N, Manion I. School-based hepatitis B immunization program: Follow-up of non-participants at first school clinic. Can J Public Health. 1997;88(3):192–96. doi: 10.1007/BF03403886. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Bloom BS, Hillman AL, Fendrick AM, Schwartz JS. A reappraisal of hepatitis B virus vaccination strategies using cost-effectiveness analysis. Ann Intern Med. 1993;118(4):298–306. doi: 10.7326/0003-4819-118-4-199302150-00009. [DOI] [PubMed] [Google Scholar]
  • 9.Krahn M, Detsky AS. Should Canada and the United States universally vaccinate infants against hepatitis B? A cost effectiveness analysis. Med Decision Making. 1993;13(1):4–20. doi: 10.1177/0272989X9301300103. [DOI] [PubMed] [Google Scholar]
  • 10.Krahn M, Guasparini R, Sherman M, Detsky AS. Cost and cost-effectiveness of a universal, school-based hepatitis B vaccination program. Am J Public Health. 1998;88(11):1638–44. doi: 10.2105/AJPH.88.11.1638. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Kerleau M, Flori YA, Nalpas JL, Lanoe JL, Berthelot P, Fardeau-Gauthier M. Analyse coût-avantage d’une politique de prévention vaccinale de l’hépatite virale B. Rev Épidémiol Santé Publ. 1995;43(1):48–60. [PubMed] [Google Scholar]
  • 12.Mangtani P, Hall AJ, Normand CE. Hepatitis B vaccination: The cost effectiveness of alternative strategies in England and Wales. J Epidemiol Community Health. 1995;49(3):238–44. doi: 10.1136/jech.49.3.238. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Margolis HS, Coleman PJ, Brown RE, Mast EE, Sheingold SH, Arevalo JA. Prevention of hepatitis B virus transmission by immunization. An economic analysis of current recommendations. JAMA. 1995;274(15):1201–8. doi: 10.1001/jama.1995.03530150025029. [DOI] [PubMed] [Google Scholar]
  • 14.Garuz R, Torrea JL, Amal JM, Forcens T, Trinxet C, Anton F, et al. Vaccination against hepatitis B virus in Spain: A cost-effectiveness analysis. Vaccine. 1997;15:1652–60. doi: 10.1016/S0264-410X(97)00083-2. [DOI] [PubMed] [Google Scholar]
  • 15.Deuson RR, Hoekstra EJ, Sedjo R, Bakker G, Melinkovich P, Daeke D, et al. The Denver School-Based Adolescent Hepatitis B Vaccination Program: A Cost Analysis With Risk Simulation. Am J Public Health. 1999;89(11):1722–27. doi: 10.2105/AJPH.89.11.1722. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 16.Wilson T. Economic evaluation of a metropolitan-wide, school-based hepatitis B vaccination program. Public Health Nurs. 2000;17(3):222–27. doi: 10.1046/j.1525-1446.2000.00222.x. [DOI] [PubMed] [Google Scholar]
  • 17.Gyorkos TW, Tannenbaum TN, Abrahamowicz M, Bédard L, Carsley J, Franco ED, et al. Evaluation of the effectiveness of immunization delivery methods. Can J Public Health. 1994;85(S1):14–30. [PubMed] [Google Scholar]
  • 18.Task Force on Community Preventive Services. Recommendations regarding interventions to improve vaccination coverage in children, adolescents, and adults. Am J Prev Med. 2000;18(1S):92–96. [PubMed] [Google Scholar]
  • 19.Centers for Disease ControlPrevention. Vaccine-preventable diseases: Improving vaccination coverage in children, adolescents, and adults. MMWR. 1999;48(RR-8):1–15. [PubMed] [Google Scholar]
  • 20.Shefer A, Briss P, Rodewald L, Bernier R, Strikas R, Yusuf H, et al. Improving immunization coverage rates: An evidence-based review of the literature. Epidemiol Rev. 1999;21(1):96–142. doi: 10.1093/oxfordjournals.epirev.a017992. [DOI] [PubMed] [Google Scholar]
  • 21.Junod B, Wietlisbach V. Méthodes et stratégies d’évaluation du programme national suisse de recherche sur la prévention des maladies cardio-vasculaires. Rev Épidémiol Santé Publ. 1981;29:315–25. [PubMed] [Google Scholar]
  • 22.Duval B, Boulianne N, De Serres G, Laflamme N, DeWals P, Masse R, et al. Comparative immunogenicity under field conditions of two recombinant hepatitis B vaccines in 8–10 year-old children. Vaccine. 2000;18(15):1467–72. doi: 10.1016/S0264-410X(99)00422-3. [DOI] [PubMed] [Google Scholar]
  • 23.Drummond MF, O’Brien B, Stoddart GL, Torrance GW. Methods for the Economic Evaluation of Health Care Programmes. Second. Oxford: Oxford University Press; 1997. [Google Scholar]

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