Table 1.

Cytotoxicity of ACS03 against various cell types by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Mean IC50 (half maximal inhibitory concentration) values were calculated from cell growth curves (n = 3).

Cell Lines *	ACS03 IC50 (µM)
HCT-116	23.11 ± 1.03
HeLa	>50
MCF-7	>50
K562	>50
HL-60	>50
HaCat	62.18 ± 1.15 a
PBMC	115.2 ± 5.82 a

^a Statistically significantly different from ACS03 treatment against HCT-116 cells (p < 0.05). Statistical analysis was performed using one-way ANOVA followed by Tukey’s test. * HCT-116: human colon carcinoma cell line; HeLa: human cervical cancer cell line; MCF-7: breast cancer cell line; K562: chronic myeloid leukemic cell line; HL-60: human promyelocytic leukemia cell line; HaCat: Human immortalized keratinocytes cell line; PBMC: peripheral blood mononuclear cells.