Table 1.
C57BL/6J WT | α9/α10 DKO | p (WT vs. DKO) | |
---|---|---|---|
Mean EAE score (day 15) | 2.7 ± 0.3 | 0.8 ± 0.2 | 0.0004 |
Peak disease severity | 2.7 ± 0.3 | 1.6 ± 0.2 | 0.006 |
Cumulative disease score | 39.3 ± 2.6 | 16.8 ± 2.3 | 0.0002 |
Incidence | 5/5 | 5/5 | - |
Key parameters from the studies illustrated in Figure 1 are summarized. P-values are for one-way ANOVA comparing WT to α9/α10 DKO mice.