Table 1.

Genotypes/allelic variants of virulence determinants encoding genes of the H. pylori strains included in this study, determined by whole genome sequencing.

H. pylori		Straingenotype											Patient
Strain ID	Genome accession N°	babA2	babB	babC	cagA	oipA	sabA	hopZ	homB	vacA	labA	hopQ	Gender	Age (yr)	Outcome
771/99	SRR6906464	+	+	+	+	on	on	on	+ (1 copy)	s1	+	II	M	10	DU
417/02	SRR6906463	-	+	-	+	on	off	on	+ (2 copies)	-	-	I/II	M	1	DU
441/02	SRP064603*	+	+	+	+	on	on	off	-	s1#	+	I	F	9	DU
559/02	SRP064604*	+	+	-	+	on	off	on	+ (1 copy)	s1	+	I	M	15	DU
1776/05	SRP064606*	+	+	+	+	on	on	off	+ (1 copy)	s1	+	I	M	15	DU
1089/03	SRP071072*	-	+	+	+	on	off	on	+ (2 copies)	s1	-	I/II	M	10	DU
1152/02	JSUZ00000000**	+	+	+	+	on	off	on	+ (2 copies)	s1	-	I	M	10	DU
1846/05	SRP071062*	+	-	+	+	on	on	on	+ (2 copies)	s1	+	I	M	13	DU
1790/05	SRR6906462	+	+	+	+	off	on	off	+ (2 copies)	s1	+	I	M	6	DU
1198/04	SRP071060*	-	+	-	+	on	off	on	+ (2 copies)	s1	+	I	M	15	DU
499/02	SRP071064*	+	+	+	+	on	off	on	+ (2 copies)	s1	+	I	M	11	GU
517/99	SRR6906460	-	+	+	-	off	on	on	-	s2	+	II	M	14	NUD
892/99	SRR6906466	-	+	-	-	off	off	on	-	s2	+	I	F	14	NUD
207/99	SRP071066*	-	+	-	-	off	off	off	-	s2	+	I/II	F	7	NUD
173/00	SRP071065*	-	+	+	-	off	on	on	-	s2	+	II	M	14	NUD
655/99	SRP071069*	-	+	-	-	off	on	on	-	s2	+	II	M	11	NUD
1786/05	JSXW00000000**	+	+	-	-	off	on	on	-	s2	+	I/II	F	11	NUD
36/00	SRR6906461	-	+	-	-	off	on	off	+ (1 copy)	s2	+	I	M	9	NUD
565/99	SRR6906459	-	+	+	-	off	on	on	+ (1 copy)	s2	+	I	M	11	NUD
1500	SRR6906465	+	+	-	-	off	off	on	-	s2	+	I/II	F	13	NUD

M, male; F, female; DU, duodenal ulcer; GU, gastric ulcer; NUD, non-ulcer dyspepsia; +, positive for that gene; -, negative for that gene; ^#, truncated s1 allele; * [44], ** [45]. The on and off frame status of the genes indicate if the gene is functional or not, respectively.