TABLE 2.

Functional enrichment of modules

Module IDa	Enriched function	Percentage in:b		Ratioc	P valued
		Module	Genome
1	Energy metabolism	0.233	0.035	6.6	>0.001
2	Nucleotide metabolism	0.089	0.022	4.0	0.020
5	Cellular processes/organismal systems/human disease	0.250	0.111	2.2	0.023
5	Hypothetical	0.563	0.368	1.5	0.027
7	Energy metabolism	0.188	0.035	5.3	0.001
7	Environmental information processing	0.125	0.032	4.0	0.020
7	Enzyme families	0.063	0.010	6.3	0.046
8	Amino acid metabolism	0.138	0.045	3.1	0.043
9	Genetic information processing	0.615	0.158	3.9	>0.001
10	Genetic information processing	0.360	0.158	2.3	0.012
11	tRNA	0.875	0.026	33.3	>0.001
12	Genetic information processing	0.552	0.158	3.5	>0.001
13	Energy metabolism	0.188	0.035	5.3	0.001
14	Phage associated	0.263	0.064	4.1	0.006
16	Genetic information processing	0.533	0.158	3.4	0.001
17	rRNA	0.154	0.003	58.6	0.001
17	Phage associated	0.385	0.064	6.0	0.001
22	Amino acid metabolism	0.250	0.045	5.5	0.002
25	Energy metabolism	0.200	0.035	5.7	0.015
34	Lipid metabolism	0.154	0.011	13.9	0.010

^aID, identifier.

^bThe percentage of N. gonorrhoeae genes with the indicated function.

^cThe ratio between the in-module percentage and the in-genome percentage.

^dThe P value of the enrichment using Fisher’s exact test.