Figure 6. Functional gene modules detected by co-expression network analysis.

(A) Topological overlap heatmap of the gene co-expression network. Each row and column represents a gene. Light color indicates low topological overlap, and on the contrary dark color denotes high topological overlap. The different side colors indicate different modules. The dendrogram suggests the clustering of these genes based on the similarity of their gene expression profiles. (B) and (C) The correlation between each module demonstrated based on eigengene. Blue represents a negative correlation, while red represents a positive correlation. (D) Scatter diagram of pathologic T stage vs. module membership for the significant genes in the turquoise module.