The April 10, 2017, article by van den Bogaard et al, entitled “Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures” (J Clin Oncol 35:1171-1178), was published with errors.
The formula’s step 2 on page 1174 in the left column should have included an exponential function. The formula was given as:
2. The cumulative incidence for each individual patient at 9 years (CI9y) can then be calculated using the following equation: CI9y = 1 – [EXP(−0.000025 × LPMHD-model)].
Instead, it should read as:
2. The cumulative incidence for each individual patient at 9 years (CI9y) can then be calculated using the following equation: CI9y = 1 – [EXP(−0.000025 × EXP(LPMHD-model))].
The formula’s step 2 on page 1175 in the right column should have included an exponential function. The formula was given as:
2. The cumulative incidence for each individual patient at 9 years (CI9y) can then be calculated using the following equation: CI9y = 1 – [EXP(−0.000223 × LPLV-V5-model)].
Instead, it should read as:
2. The cumulative incidence for each individual patient at 9 years (CI9y) can then be calculated using the following equation: CI9y = 1 – [EXP(−0.000223 × EXP(LPLV-V5-model))].
The formula’s step 3 on page 1175 in the right column was given as:
3. The 9-year excess cumulative risk (CER9y) can then be calculated by using Equation 2 minus the CI9y assuming an MHD of 0 Gy (CI9y-0Gy): CER9y = CI9y - CI9y-0Gy.
Instead, it should read as:
3. The 9-year excess cumulative risk (CER9y) can then be calculated by using Equation 2 minus the CI9y assuming an LV-V5 of 0% (CI9y-0%): CER9y = CI9y - CI9y-0%.
Figures 3B, 3C and 3D on page 1176 contain errors due to an incorrect B-coefficient. The correct B-coefficient is 0.711 (table 3).
The online version has been corrected in departure from the print. The authors apologize for the errors.