Table 2.
Effect of nHA, nCh/HA and nAg/HA as well as ALN on serum SOST, BALP and BSP levels in osteoporotic rats.
| Groups | SOST (pg/mL) | BALP (ng/mL) | BSP (pg/mL) |
|---|---|---|---|
| Gonad-intact control | 151.38 ± 4.57 | 23.313 ± 1.47 | 50.00 ± 2.49 |
| Osteoporotic | 225.15 ± 12.10*a (48.74%) | 34.52 ± 1.35*a (48.10%) | 87.51 ± 6.32*a (75.01%) |
| nHA | 188.83 ± 2.26*b (-16.13%) | 24.90 ± 1.68*b (-27.86%) | 67.01 ± 3.94*b (-23.42%) |
| nCh/HA | 189.81 ± 6.16*b (-15.69%) | 25.97 ± 0.87*b (-24.76%) | 68.06 ± 1.66*b (-22.22%) |
| nAg/HA | 194.91 ± 3.00*b (-13.43%) | 26.42 ± 0.78*b (-23.45%) | 68.77 ± 2.97*b (-21.41%) |
| ALN | 213.23 ± 7.12*c*d (-5.29%) | 31.17 ± 1.93*c*d*e (-9.41%) | 75.00 ± 2.00*b (-14.29%) |
Data are expressed as Mean ± S.E for 8 rats/group.
*a: Significant change at P < 0.05 in comparison with the gonad-intact group.
*b: Significant change at P < 0.05 in comparison with the osteoporotic group.
*c: Significant change at P < 0.05 in comparison with the nHA-treated group.
*d: Significant change at P < 0.05 in comparison with the nCh/HA-treated group.
*e: Significant change at P < 0.05 in comparison with the nAg/HA-treated group.