Figure 2.

The association between BLK and systemic lupus erythematosus (SLE). The methylation level of cg09528494 in BLK and BLK gene expression were directly associated with SLE according to the summary data‐based Mendelian randomization (SMR) analysis based on methylation quantitative trait loci (meQTL) data from the study conducted by McRae et al.14 (a) and expression quantitative trait loci (eQTL) data from the CAGE study (b), GTEx project (c) and the study conducted by Westra et al.17 (d), respectively.