Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The phosphatidylinositol 3-kinase (PI3K)/AKT/mTOR pathway. Main signaling pathway initiated by growth factors that activate tyrosine kinase to initiate a series of downstream reactions that trigger P13K to generate second messenger (PIP3). PIP3 activates downstream signaling cascade important in cell proliferation, migration, transport, and survival.
