Figure 2.

A schematic of HPV (human papillomavirus virion). A double-stranded DNA genome (red) is surrounded by the capsid, which is composed of two proteins: the major capsid protein (L1, shown in light green) and the minor capsid protein (L2, shown in brown color). The L1 protein forms pentamers, and L2 protein is inserted on vertices of the pentamers. Seventy-two copies of the pentamers and about 12–72 copies of L2 protein assemble to form a virion.