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Trifolium pratense isoflavones as modulators of cell migration—the proposed mechanism of action. They possess cytoprotective activity against ROS generation, stiffen cellular membrane, induce apoptotic type cell death and influence expression of MMP9 and VEGF. ERα/β—estrogen receptor α/β; ERE—estrogen responsive element; MMP9—matrix metalloproteinase 9; VEGF—vascular endothelial growth factor.
