Fig. 5.

The effect of chronic oxytocin treatment during abstinence on 0.3 mg/kg (a–c) and 1.0 mg/kg (d–f) METH-primed reinstatement to METH-seeking behaviour in ShA and LgA trained male and female rats. a, d Active lever presses. b, e Inactive lever presses. c, f Locomotor activity. METH was administered IP immediately prior to initiation of the reinstatement session. Overlaid graphs depict data from the respective extinction day prior to each test. *p < 0.05 compared with respective ShA group. ^#p < 0.05 compared with respective saline group. ^{^}p < 0.05 compared with extinction day prior to test. Data are presented as mean ± SEM. n = 8/group.