Table 4.
Diagnostic potential of the four EV-miRNAs, individually and combined, based on the ROC curve analysis.
| EV-miRNA | Comparison | AUC | p-Value | Cutoff | Sensitivity | Specificity |
|---|---|---|---|---|---|---|
| miR-142-5p, miR-320a and miR-4433b-5p panel | CT versus CA | 0.8387 | <0.0001 | 0.4504 | 93.55% | 68.75 |
| miR-320a | CT versus CA | 0.8063 | <0.001 | 0.0060 | 93.33% | 68.75% |
| miR-142-5p | CT versus CA | 0.7964 | <0.001 | 0.6435 | 87.10% | 81.25% |
| miR-4433b-5p | CT versus CA | 0.7964 | <0.002 | 0.7578 | 87.10% | 75% |
| miR-142-5p and miR-320a panel | CT versus LA | 0.9410 | <0.0001 | 0.0871 | 100% | 93.80% |
| miR-142-5p | CT versus LA | 0.9180 | <0.0001 | 0.7926 | 100% | 81.25% |
| miR-320a | CT versus LA | 0.8828 | <0.001 | 0.0065 | 93.75% | 68.75% |
| miR-4433b-5p | CT versus LA | 0.8672 | <0.001 | 0.7743 | 93.75% | 75% |
| miR-142-5p | TNBC versus LA | 0.9208 | <0.0001 | 0.6435 | 87.10% | 81.25% |
| miR-150-5p | TNBC versus LA | 0.8667 | <0.001 | 39.3800 | 80% | 75% |
Only AUC > 0.79 values were represented.