Table 4. Univariate and multivariate analyses of overall survival in TCGA.

Parameters	Univariate analysis				Multivariate analysis
	p-value	HR	95% CI		p-value	HR	95% CI
Age	0.755	1.054	0.756	1.470
Gender	0.588	0.922	0.697	1.237
Smoking history	0.258	0.690	0.363	1.312
TNM tumor stage	<0.001**	1.694	1.472	1.948	0.068	1.458	0.973	2.186
T	<0.001**	1.547	1.283	1.866	0.072	1.231	0.982	1.544
N	<0.001**	1.709	1.438	2.030	0.285	1.214	0.851	1.731
M	0.003**	2.257	1.316	3.869	0.621	0.775	0.282	2.128
DSG2	0.001**	1.638	1.214	2.209	0.461	1.151	0.792	1.673

Notes.

^**p < 0.01.

T

tumor

N

node

M

metastasis

TNM

tumor-node-metastasis

HR

hazard ratio

CI

confidence interval