Table 5. GO enrichment and KEGG analysis of the co-expressed genes with DSG2 in LUA.
Category/term | Count | p-value | FDR |
---|---|---|---|
Biological process | |||
GO: 0051301 ∼cell division | 26 | 0.074 | <0.001 |
GO: 0007067 ∼mitotic nuclear division | 22 | 0.063 | <0.001 |
GO: 0007059 ∼chromosome segregation | 10 | 0.029 | <0.001 |
GO: 0007062 ∼sister chromatid cohesion | 11 | 0.031 | <0.001 |
GO: 0007018 ∼microtubule-based movement | 9 | 0.026 | 0.005 |
GO: 0019886 ∼antigen processing and presentation of exogenous peptide antigen via MHC class II | 9 | 0.026 | 0.013 |
Cellular component | |||
GO: 0005829 ∼cytosol | 73 | <0.001 | <0.001 |
GO: 0030496 ∼midbody | 14 | <0.001 | <0.001 |
GO: 0016020 ∼membrane | 54 | <0.001 | <0.001 |
GO: 0005737 ∼cytoplasm | 91 | <0.001 | <0.001 |
GO: 0005730 ∼nucleolus | 28 | <0.001 | <0.001 |
GO: 0005813 ∼centrosome | 19 | <0.001 | 0.001 |
GO: 0051233 ∼spindle midzone | 6 | <0.001 | 0.002 |
GO: 0005871 ∼kinesin complex | 8 | <0.001 | 0.002 |
GO: 0000776 ∼kinetochore | 9 | <0.001 | 0.004 |
GO: 0000922 ∼spindle pole | 10 | <0.001 | 0.004 |
Molecular function | |||
GO: 0005524 ∼ATP binding | 42 | <0.001 | <0.001 |
GO: 0005515 ∼protein binding | 133 | <0.001 | <0.001 |
GO: 0003777 ∼microtubule motor activity | 9 | <0.001 | 0.004 |
GO: 0008017 ∼microtubule binding | 13 | <0.001 | 0.006 |
GO: 0008574 ∼ATP-dependent microtubule motor activity, plus-end-directed | 5 | <0.001 | 0.044 |
Pathway | |||
hsa04110: Cell cycle | 11 | <0.001 | 0.002 |
Notes.
- FDR
- false discovery rate
- hsa
- Homo sapiens