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. 2019 Sep 17;15(3):307–322. doi: 10.1080/15592294.2019.1666652

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 3. — Impact of VC on genomic 5-hmdC/dC levels in IDH1^+/+ and IDH1^R132H/+ cells.

(a,b) Quantification of 5-hmdC/dC levels in IDH1^+/+ and IDH1^R132H/+ treated for 48 h with increasing concentrations of VC as indicated (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 – significant results; error bars = SD; n = 3).