Supplementary Fig. S4.

Added volumes of 7.8 Gy isodose surface volume(the physical dose resulting in the aim dose of 85 Gy EQD2 for the D90 CTV_HR). Discrete colour scale showing the number of centres achieving the 7.8 Gy in the given region. Each step in the discrete colour scale signifies one centre less, starting with dark red, all centres, to light blue, one centre. Contours visible are GTV_res (magenta) CTV_HR (pink) CTV_IR (blue) and bladder rectum and bowel. The figure illustrates the differences in the cranial and caudal part. Left: first plan Right: second plan.

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