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. 2020 Feb 7;267(3):713–714. doi: 10.1007/s00415-020-09715-5

Correction to: Analysis of autonomic outcomes in APOLLO, a phase III trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis

Alejandra González-Duarte 1,, John L Berk 2, Dianna Quan 3, Michelle L Mauermann 4, Hartmut H Schmidt 5, Michael Polydefkis 6, Márcia Waddington-Cruz 7, Mitsuharu Ueda 8, Isabel M Conceição 9, Arnt V Kristen 10, Teresa Coelho 11, Cécile A Cauquil 12, Céline Tard 13, Madeline Merkel 14, Emre Aldinc 14, Jihong Chen 14, Marianne T Sweetser 14, Jing Jing Wang 14, David Adams 15
PMCID: PMC7035215  PMID: 32030522

Correction to: Journal of Neurology 10.1007/s00415-019-09602-8

The original version of this article unfortunately contained a mistake in Table 1.

Table 1.

Disease characteristics of autonomic endpoints at baseline

Characteristic Placebo (n = 77) Patisiran (n = 148) Total (n = 225)
COMPASS-31 total score (range 0–100), mean (± SD) 30.3 (16.4) 30.6 (17.6) 30.5 (17.1)
 Orthostatic intolerance (range: 0–40), mean (± SD) 13.2 (11.2) 14.2 (10.8) 13.8 (10.9)
 Vasomotor (range 0–5), mean (± SD) 1.0 (1.4) 0.9 (1.44) 1.0 (1.4)
 Secretomotor (range 0–15), mean (± SD) 4.9 (3.7) 4.2 (3.7) 4.4 (3.7)
 Gastrointestinal (range 0–25), mean (± SD) 8.1 (3.5) 8.2 (4.3) 8.1 (4.1)
 Bladder (range 0–10), mean (± SD) 1.9 (2.7) 2.0 (2.5) 2.0 (2.5)
 Pupillomotor (range 0–5), mean (± SD) 1.1 (1.1) 1.2 (1.2) 1.2 (1.2)
mBMI (kg/m2 × g/L), mean (± SD) 989.9 (214.2) 969.7 (210.5) 976.6 (211.5)
 BMI (kg/m2), mean (± SD) 23.6 (4.3) 23.0 (4.4) 23.2 (4.4)
 Albumin (g/L), mean (± SD) 41.8 (3.4) 42.1 (3.5) 42.0 (3.5)
 Weight (kg), mean (± SD) 67.5 (15.7) 67.3 (16.6) 67.4 (16.3)
mNIS + 7 total score (range 0–304), mean (± SD) 74.6 (37.0) 80.9 (41.5) 78.8 (40.1)
 Postural blood pressure (range 0–2), mean (± SD) 0.6 (0.7) 0.7 (0.8) 0.6 (0.8)
Norfolk QOL-DN total score (range − 4 to 136), mean (± SD) 55.5 (24.3) 59.6 (28.2) 58.3 (27.0)
 Autonomic neuropathy domain (range 0–12), mean (± SD) 2.9 (2.9) 3.0 (2.8) 3.0 (2.8)

BMI body mass index, COMPASS-31 Composite Autonomic Symptom Score-31, mBMI modified body mass index, mNIS + 7 modified Neuropathy Impairment Score + 7, Norfolk QOL-DN Norfolk Quality of Life-Diabetic Neuropathy

Units for albumin were given as g/dL. It should be g/L.


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