Figure 5.

Differentially Expressed Genes in the Striatum

Hierarchical clustering analysis of differentially expressed transcripts in the striatum of Thra^AMI/gn mice and control littermates at PND7 and PND14. The analysis is restricted to 260 genes for which the fold-change is > 2 or <0.5 (adjusted p value < 0.05) for at least one developmental stage. High expression is in yellow, low expression is in blue, average in black. Note that the changes in gene expression between PND7 and PND14 are more conspicuous in control than in mutant mice, suggesting that a maturation process is blunted by the mutation. See also Figure S8 and Tables S2 and S4.