Table 2. Comparison of pathological characteristics between the two groups.
APLA2R-ab (−) (N = 59) | APLA2R-ab (+) (N = 170) | P value | |
---|---|---|---|
Pathological stage (%) | |||
I | 45/59 (76.27%) | 112/170 (65.88%) | 0.454 |
II | 14/59 (23.72%) | 55/170 (32.35%) | 0.321 |
III + IV | 0 | 2/170 (1.18%) | 0.293 |
Tissue IgG | 2.46 ± 0.83 | 2.37 ± 0. 89 | 0.486 |
Tissue IgM | 0.36 ± 0.79 | 0.38 ± 0.69 | 0.810 |
Tissue IgA | 0.12 ± 0.50 | 0.23 ± 0.61 | 0.182 |
Tissue C3 | 1.09 ± 0.87 | 1.19 ± 0.94 | 0.459 |
Tissue Fib | 0.08 ± 0.39 | 0.15 ± 0.52 | 0.264 |
Tissue C1q | 0.53 ± 0.80 | 0.50 ± 0.71 | 0.796 |
Pathological characteristics | |||
Global sclerosis | 35/59 (59.32%) | 88/170 (51.76%) | 0.337 |
Glomerular mesangial hyperplasia | 16/59 (27.12%) | 64/170 (37.65%) | 0.124 |
Crescents | 2/59 (3.38%) | 0 | 0.159 |
Hyperplasia endothelialitis | 4/59 (6.78%) | 7/170 (4.12%) | 0.418 |
Acute renal tubular lesions | 2/59 (3.39%) | 20/170 (11.76%) | 0.015* |
Chronic renal tubular lesions | 2/59 (3.39%) | 21/170 (13.53%) | 0.010** |
Inflammatory cell infiltration | 3/59 (5.08%) | 23/170 (13.53%) | 0.031* |
Vascular disease | 21/59 (35.59%) | 57/170 (33.53%) | 0.796 |
Notes.
Compared with the PLa2R− group and the PLA2R+ group, P∗ < 0.05, P∗∗ < 0.01.